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MEK-IN-6

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MEK-IN-6 Suppliers list
Company Name: Afflon Pharmaceutical (Sichuan) Co., Ltd.  Gold
Tel: 17336178085
Email: 1684779048@qq.com
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Company Name: Henan Yinuokai New Materials Co., Ltd  
Tel: 15565215982 15565215982
Email: 15565215982@163.com
Company Name: ChemOrigin Pharm  
Tel: 15026428026 19002516454
Email: ChemOrigin@126.com
Company Name: TargetMol Chemicals Inc.  
Tel: 13564774135
Email: marketing@targetmol.com

MEK-IN-6 manufacturers

  • MEK-IN-6
  • MEK-IN-6 pictures
  • $2180.00
  • 2026-07-27
  • CAS:2845151-86-0
  • Purity:
  • Supply Ability: 10g
MEK-IN-6 Basic information
Product Name:MEK-IN-6
Synonyms:MEK-IN-6;2,7-Naphthyridine-1,6(2H,7H)-dione, 8-[[2-fluoro-4-(methylthio)phenyl]amino]-3,4-dihydro-2-(2-hydroxyethoxy)-7-methyl-;MEK inhibitor Polfurmetinib;Polfurmetinib
CAS:2845151-86-0
MF:C18H20FN3O4S
MW:393.43
EINECS:
Product Categories:
Mol File:2845151-86-0.mol
MEK-IN-6 Structure
MEK-IN-6 Chemical Properties
Boiling point 574.455±60.00 °C(Press: 760.00 Torr)(predicted)
density 1.451±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka14.335±0.10(predicted)
form Solid
color White to light yellow
Safety Information
MSDS Information
MEK-IN-6 Usage And Synthesis
UsesMEK-IN-6 (Example 69) is a MEK inhibitor. MEK-IN-6 inhibits ERK1/2 (Thr202/Tyr204) phosphorylation in A375 cells (IC50: 2 nM). MEK-IN-6 can be used for research of cancer[1].
IC 50MEK
References[1] Shelley Allen, et al. 3,4-dihydro-2,7-naphthyridine-1,6(2h,7h)-diones as mek inhibitors. Patent. WO2022208391.
MEK-IN-6 Preparation Products And Raw materials
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