| Company Name: |
Fuan Bio |
| Tel: |
15002819872 |
| Email: |
2845971812@qq.com |
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| Product Name: | BIMAX2 | | Synonyms: | BIMAX2;L-Aspartic acid, L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-lysyl-L-arginyl-L-lysyl-L-arginyl-L-α-glutamyl-L-tryptophyl-L-α-aspartyl-L-α-aspartyl-L-α-aspartyl-L-α-aspartyl-L-α-aspartyl-L-prolyl-L-prolyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-arginyl-L-leucyl- | | CAS: | 1105053-46-0 | | MF: | C146H254N64O41 | | MW: | 3561.99 | | EINECS: | | | Product Categories: | | | Mol File: | 1105053-46-0.mol |  |
| | BIMAX2 Chemical Properties |
| density | 1.59±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | | Sequence | Arg-Arg-Arg-Arg-Arg-Arg-Lys-Arg-Lys-Arg-Glu-Trp-Asp-Asp-Asp-Asp-Asp-Pro-Pro-Lys-Lys-Arg-Arg-Arg-Leu-Asp |
| | BIMAX2 Usage And Synthesis |
| Uses | BIMAX2 is a high affinity nuclear localization signal (NLS) peptide. BIMAX2 can mimic the activity of the classical nuclear localization signal (cNLS) and competitively bind to importin α, thereby inhibiting the binding of cNLS-cargo proteins to importin α. BIMAX2 can be used to study the role of RBBP4 in regulating nuclear import efficiency and cell senescence[1]. | | References | [1] Tsujii, et al. "Retinoblastoma-binding protein 4-regulated classical nuclear transport is involved in cellular senescence." Journal of Biological Chemistry 290.49 (2015): 29375-29388. DOI:10.1074/jbc.M115.681908 |
| | BIMAX2 Preparation Products And Raw materials |
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