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| | (+/-)-CGP-12177 HYDROCHLORIDE Basic information |
| Product Name: | (+/-)-CGP-12177 HYDROCHLORIDE | | Synonyms: | (+/-)-CGP-12177 HYDROCHLORIDE;CGP 12177 HYDROCHLORIDE;4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE HYDROCHLORIDE;CGP12177HCl;CGP 12177 hydochloride;CGP 12177;4-(3-tert-Butylamino-2-Hydroxypropoxy)benzimidazol-2-One;4-(3-tert-Butylamino-2-hydroxypropoxy)-1H-benzimidazol-2(3H)-one | | CAS: | 81047-99-6 | | MF: | C14H21N3O3 | | MW: | 279.33 | | EINECS: | | | Product Categories: | Adrenoceptor | | Mol File: | 81047-99-6.mol |  |
| | (+/-)-CGP-12177 HYDROCHLORIDE Chemical Properties |
| Melting point | >256°C (dec.) | | Boiling point | 376.3±37.0 °C(Predicted) | | density | 1.179 | | storage temp. | Store at RT | | solubility | DMSO: >10 mg/mL | | form | solid | | pka | 11.48±0.30(Predicted) | | color | white |
| | (+/-)-CGP-12177 HYDROCHLORIDE Usage And Synthesis |
| Uses | CGP 12177 Hydrochloride is a selective β3-adrenoceptor agonist. | | Definition | ChEBI: A benzimidazole that is benzimidazol-2-one substituted at position 4 by a 3-(tert-butylamino)-2-hydroxypropoxy group. | | Biological Activity | Partial agonist at β 3 -adrenoceptors. β 1 - and β 2 -adrenoceptor antagonist (K i values are 0.9, 4 and 88 nM for β 1 , β 2 and β 3 receptors respectively). |
| | (+/-)-CGP-12177 HYDROCHLORIDE Preparation Products And Raw materials |
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