2':3'-CYCLIC NADP SODIUM SALT

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2':3'-CYCLIC NADP SODIUM SALT Basic information
Product Name:2':3'-CYCLIC NADP SODIUM SALT
Synonyms:2':3'-CYCLIC NADP SODIUM SALT;BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE 2':3'-CYCLIC MONOPHOSPHATE SODIUM SALT;B-nicotinamide adenine dinucleotide*2':3'-cyclic;2':3'-cyclic nadp;β-nicotinamide adenine dinucleotide 2':3'-cyclic monophosphate disodium salt hydrate;β-Nicotinamide adenine dinucleotide 2μ:3μ-cyclic monophosphate hydrate disodium salt;Adenosine5'-(trihydrogen diphosphate), cyclic 2',3'-(hydrogen phosphate), P'→5'-ester with3-(aminocarbonyl)-1-b-D-ribofuranosylpyridinium inner salt, disodium salt;2',3'-cyclic NADP+ (sodium salt)
CAS:100929-77-9
MF:C21H25N7NaO16P3
MW:747.37
EINECS:
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Mol File:100929-77-9.mol
2':3'-CYCLIC NADP SODIUM SALT Structure
2':3'-CYCLIC NADP SODIUM SALT Chemical Properties
storage temp. −20°C
solubility Water: Soluble
Safety Information
Hazard Codes T
Risk Statements 23/24/25-36/37/38
Safety Statements 22-26-36-45
WGK Germany 3
MSDS Information
2':3'-CYCLIC NADP SODIUM SALT Usage And Synthesis
Uses2',3'-Cyclic NADP disodium (2',3'-cNADP+; β-Nicotinamide adenine dinucleotide-2',3'-cyclic phosphate) is a substrate for 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP), an enzyme abundant in myelin. It has been used in a coupled enzyme assay to quantify CNP activity. 2',3'-Cyclic NADP disodium (5 μM) increases calcium overload-induced calcium release and prevents calcium-induced swelling in rat brain mitochondria.
References[1] Sogin, et al. 2',3'-Cyclic NADP as a substrate for 2',3'-cyclic nucleotide 3'-phosphohydrolase. J. Neurochem. 27(6), 1333-1337 (1976).
[2] TAMARA AZARASHVILI. Ca2+-dependent permeability transition regulation in rat brain mitochondria by 2’,3’-cyclic nucleotides and 2’,3’-cyclic nucleotide 3’-phosphodiesterase.[J]. American journal of physiology. Cell physiology, 2009, 296 6: C1428-39. DOI: 10.1152/ajpcell.00006.2009
2':3'-CYCLIC NADP SODIUM SALT Preparation Products And Raw materials
Tag:2':3'-CYCLIC NADP SODIUM SALT(100929-77-9) Related Product Information
adenosine5’-diphosphate,monosodiumsaltdihydrate β-Nicotinamide adenine dinucleotide sodium salt β-Nicotinamide Mononucleotide ETHYL PHOSPHATE ADENOSINE5'-MONOPHOSPHATESODIUMSALT ADENOSINE-2',3'-CYCLIC PHOSPHATE 2':3'-CYCLIC NADP SODIUM SALT 2'-DEOXYADENOSINE-3'-MONOPHOSPHATE 2'-DEOXYADENOSINE-3'-MONOPHOSPHATE AMMONIUM SALT β-Nicotinamide adenine dinucleotide ADENOSINE 5'-DIPHOSPHATE, MONOSODIUM SALT DIHYDRATE, 98