Ethyl 5-(4-tert-butoxycarbonyl-1-piperazinyl)benzofuran-2-carboxylate

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Ethyl 5-(4-tert-butoxycarbonyl-1-piperazinyl)benzofuran-2-carboxylate Basic information
Uses
Product Name:Ethyl 5-(4-tert-butoxycarbonyl-1-piperazinyl)benzofuran-2-carboxylate
Synonyms:Ethyl 5-(4-tert-butoxycarbonyl-1-piperazinyl)benzofuran-2-carboxylate;4-[2-(Ethoxycarbonyl)-5-benzofuranyl]-1-piperazinecarboxylic acid tert-butyl ester;EOS-60443;ethyl 5-(4-tert-butoxycarbonyl-1-piperazinyl)benzofuran-2-carboxylate(C3);tert-butyl 4-(2-ethoxycarbonyl-1-benzofuran-5-yl)piperazine-1-carboxylate;tert-Butyl 4-(2-(ethoxycarbonyl)benzofuran-5-yl)piperazine-1-carboxylate;1-Piperazinecarboxylic acid, 4-[2-(ethoxycarbonyl)-5-benzofuranyl]-, 1,1-diMethylethyl ester;1-Boc-4-(2-(ethoxycarbonyl)benzofuran-5-yl)piperazine
CAS:183288-43-9
MF:C20H26N2O5
MW:374.43
EINECS:695-998-3
Product Categories:
Mol File:183288-43-9.mol
Ethyl 5-(4-tert-butoxycarbonyl-1-piperazinyl)benzofuran-2-carboxylate Structure
Ethyl 5-(4-tert-butoxycarbonyl-1-piperazinyl)benzofuran-2-carboxylate Chemical Properties
Boiling point 494.0±45.0 °C(Predicted)
density 1.202
storage temp. 2-8°C
pka0.13±0.70(Predicted)
AppearanceOff-white to light yellow Solid
InChIInChI=1S/C20H26N2O5/c1-5-25-18(23)17-13-14-12-15(6-7-16(14)26-17)21-8-10-22(11-9-21)19(24)27-20(2,3)4/h6-7,12-13H,5,8-11H2,1-4H3
InChIKeyUGJBHBXXMCVEIH-UHFFFAOYSA-N
SMILESN1(C(OC(C)(C)C)=O)CCN(C2=CC=C3OC(C(OCC)=O)=CC3=C2)CC1
Safety Information
MSDS Information
Ethyl 5-(4-tert-butoxycarbonyl-1-piperazinyl)benzofuran-2-carboxylate Usage And Synthesis
UsesEthyl 5-(4-tert-butoxycarbonyl-piperazin-1-yl)benzofuran-2-carboxylate can be used to prepare 5-(1-piperazinyl)-benzofuran-2-carboxamide. 5-(1-piperazinyl)-benzofuran-2-carboxamide or its acid addition salt is a key intermediate in the synthesis of vilazone.
Ethyl 5-(4-tert-butoxycarbonyl-1-piperazinyl)benzofuran-2-carboxylate Preparation Products And Raw materials
Tag:Ethyl 5-(4-tert-butoxycarbonyl-1-piperazinyl)benzofuran-2-carboxylate(183288-43-9) Related Product Information
2-Benzofurancarboxylic acid, 5-(1-piperazinyl)-, ethyl ester, (Hydrochloride), hydrate (1:2:1) Vilazodone Intermediate 5-(1-piperazinyl)-2-Benzofurancarboxylic acid ethyl ester Monohydrochloride 5-(4-tert-Butoxycarbonyl-2-piperazinyl)benzofuran-2-carboxaMide 5-(piperazin-1-yl)benzofuran-2-carboxylic acid 5-piperazin-1-yl-1-benzofuran-2-carboxamide