Des[2'-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde

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Des[2'-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde Basic information
Product Name:Des[2'-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde
Synonyms:Des[2'-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde;2-n-Butyl-4-chloro-1-[(2'-cyanobiphenyl-4-yl)methyl]imidazole-5-carboxaldehyde;[1,1'-Biphenyl]-2-carbonitrile, 4'-[(2-butyl-4-chloro-5-formyl-1H-imidazol-1-yl)methyl]-;2-[4-[(2-butyl-4-chloro-5-formylimidazol-1-yl)methyl]phenyl]benzonitrile;Losartan Related compund A;Losartan Related Compound A 4’-[(2-Butyl-4-chloro-5-formyl-1H-imidazol-1-yl)methyl]-[1,1’- Biphenyl]-2-carbonitrile;Losartan Potassium Related Compound A/Losartan Impurity 35
CAS:124750-67-0
MF:C22H20ClN3O
MW:377.87
EINECS:
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Mol File:124750-67-0.mol
Des[2'-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde Structure
Des[2'-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde Chemical Properties
Melting point 99 °C(Solv: methanol (67-56-1))
Boiling point 590.1±50.0 °C(Predicted)
density 1.18±0.1 g/cm3(Predicted)
storage temp. Refrigerator
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
pka1.54±0.60(Predicted)
color White to Off-White
Safety Information
MSDS Information
Des[2'-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde Usage And Synthesis
UsesDes[2’-(1H-tetrazol-5-yl)] 2-Cyanolosartan carboxaldehyde is a derivative of Losartan carboxaldehyde (L470505). Des[2’-(1H-tetrazol-5-yl)] 2-Cyanolosartan carboxaldehyde is also used as reagent to synthesize Losartan Potassium (L470500), a an angiotensin II antagonist and is commonly used to significantly reduce risk of new onset atrial fibrillation and associated stroke in high-risk patients.
Des[2'-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde Preparation Products And Raw materials
Preparation Products4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile-->Losartan potassium
Tag:Des[2'-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde(124750-67-0) Related Product Information
Losartan Carboxaldehyde 3-Butyl-1-chloro-5,10-dihydro-8-(2-cyanophenyl)imidazol-[1,5-b]isoquinoline N-(4-Bromobenzyl)-2-butyl-4-chloro-1H-imidazole-5-carboxyaldehyde Des[2'-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde 4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile