Z-Ile-Glu-Pro-Phe-OMe manufacturers
- CH 5450
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- $30.00
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2026-07-15
- CAS:252557-97-4
- Purity: 95.93%
- Supply Ability: 10g
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| | Z-Ile-Glu-Pro-Phe-OMe Basic information |
| Product Name: | Z-Ile-Glu-Pro-Phe-OMe | | Synonyms: | Z-Ile-Glu-Pro-Phe-OMe;CH-5450
(Z-Ile-Glu-Pro-Phe-CO2Me);CH 5450;Z-ILE-GLU-PRO-PHE-CO2ME;Z-Ile-Glu-Pro-Phe-Ome, BR;L-Phenylalanine, N-[(phenylmethoxy)carbonyl]-L-isoleucyl-L-α-glutamyl-L-prolyl-, 4-methyl ester;CH5450,inhibit,MAB elastase 2,CH 5450,Inhibitor,Ang I,chymase,CH-5450;Z-IEPF-OMe | | CAS: | 252557-97-4 | | MF: | C34H44N4O9 | | MW: | 652.75 | | EINECS: | | | Product Categories: | | | Mol File: | 252557-97-4.mol |  |
| | Z-Ile-Glu-Pro-Phe-OMe Chemical Properties |
| Boiling point | 928.4±65.0 °C(Predicted) | | density | 1.251±0.06 g/cm3(Predicted) | | pka | 4.48±0.10(Predicted) | | form | Solid | | color | White to off-white | | Sequence | Z-Ile-Glu-Pro-Phe-OMe |
| | Z-Ile-Glu-Pro-Phe-OMe Usage And Synthesis |
| Uses | CH 5450 (Z-Ile-Glu-Pro-Phe-Ome) is a selective short peptide human cardiac chymase inhibitor. CH-5450 inhibits the action of rat MAB elastase 2 on substrate Ang I with an IC50 value of 49 μM and N-succinyl-Ala-Ala-Pro-Phe-p-nitroanilide with an IC50 value of 4.8 μM[1]. | | References | [1] Carlos F Santos, et al. Kinetic characterization and inhibition of the rat MAB elastase-2, an angiotensin I-converting serine protease. Can J Physiol Pharmacol. 2002 Jan;80(1):42-7. DOI:10.1139/y02-004 |
| | Z-Ile-Glu-Pro-Phe-OMe Preparation Products And Raw materials |
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