- HUHS015
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- $61.00 / 5mg
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2026-02-02
- CAS:1453097-13-6
- Min. Order:
- Purity: 99.33%
- Supply Ability: 10g
- HUHS015
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- $1.00 / 1KG
-
2019-12-26
- CAS:1453097-13-6
- Min. Order: 1KG
- Purity: 97%-99.9%
- Supply Ability: 100kg
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| | HUHS015 Basic information |
| Product Name: | HUHS015 | | Synonyms: | HUHS015;4-Benzyl-3-methyl-1-(6-methyl-1H-benzo[d]imidazol-2-yl)-1H-pyrazol-5-ol;HUHS-015;HUHS 015;1H-Pyrazol-5-ol, 3-methyl-1-(6-methyl-1H-benzimidazol-2-yl)-4-(phenylmethyl)-;prostate,ALKBH3,antigen-1,HUHS015,HUHS 015,PCA-1,inhibit,HUHS-015,Inhibitor,cancer;HUHS015, 10 mM in DMSO | | CAS: | 1453097-13-6 | | MF: | C19H18N4O | | MW: | 318.37 | | EINECS: | | | Product Categories: | | | Mol File: | 1453097-13-6.mol |  |
| | HUHS015 Chemical Properties |
| Boiling point | 585.2±42.0 °C(Predicted) | | density | 1.30±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO:34.0(Max Conc. mg/mL);106.79(Max Conc. mM) | | form | A crystalline solid | | pka | 8.12±0.50(Predicted) | | color | White to off-white |
| | HUHS015 Usage And Synthesis |
| Uses | HUHS 015 is used in preparation of arylpyrazolol derivatives as antigen-1 (PCA-1/ALKBH3) inhibitors for anti-prostate cancer drugs. | | in vivo | HUHS015 potently suppresses the growth of DU145 cells in a mouse xenograft model[1].
HUHS015 displays 7.2% bioavailability (BA) in rats after oral administration[1].
| Animal Model: | Nude mice[1] | | Dosage: | 32 mg/kg | | Administration: | Subcutaneous injection; daily; 6 days | | Result: | Has inhibitory effect on the growth of subcutaneously implanted DU145, without limiting weight gains after a 6 days continuous administration. |
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| | HUHS015 Preparation Products And Raw materials |
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