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| | N-(Boc-PEG3)-N-Bis-(PEG3-acid) Basic information |
| Product Name: | N-(Boc-PEG3)-N-Bis-(PEG3-acid) | | Synonyms: | N-(Boc-PEG3)-N-Bis-(PEG3-acid);5,8,11,17,20,23-Hexaoxa-2,14-diazahexacosanedioic acid, 14-[2-[2-[2-(2-carboxyethoxy)ethoxy]ethoxy]ethyl]-, 1-(1,1-dimethylethyl) ester;13-(2,2-Dimethyl-4-oxo-3,8,11,14-tetraoxa-5-azahexadecan-16-yl)-4,7,10,16,19,22-hexaoxa-13-azapentacosanedioic acid | | CAS: | 2055042-61-8 | | MF: | C31H60N2O15 | | MW: | 700.81 | | EINECS: | | | Product Categories: | | | Mol File: | 2055042-61-8.mol |  |
| | N-(Boc-PEG3)-N-Bis-(PEG3-acid) Chemical Properties |
| Boiling point | 769.7±60.0 °C(Predicted) | | density | 1.155±0.06 g/cm3(Predicted) | | solubility | DMSO : 100 mg/mL (142.69 mM; Need ultrasonic) | | pka | 3.97±0.10(Predicted) | | form | Viscous Liquid | | color | Yellow to brown |
| | N-(Boc-PEG3)-N-Bis-(PEG3-acid) Usage And Synthesis |
| Description | N-(Boc-PEG3)-N-bis(PEG3-acid) is a branched PEG molecule that can be conjugated with amine containing molecule. Boc can be deprotected under acidic conditions. | | Uses | N-(Boc-PEG3)-N-bis(PEG3-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | N-(Boc-PEG3)-N-Bis-(PEG3-acid) Preparation Products And Raw materials |
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