H2N-PEG6-CH2COOtBu manufacturers
- NH2-PEG6-C1-Boc
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2026-07-16
- CAS:297162-50-6
- Purity: ≥98%
- Supply Ability: 10g
- NH2-PEG6-CH2COOtBu
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2026-01-29
- CAS:297162-50-6
- Min. Order: 1g
- Purity: 98%
- Supply Ability: 300kg
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| | H2N-PEG6-CH2COOtBu Basic information |
| Product Name: | H2N-PEG6-CH2COOtBu | | Synonyms: | H2N-PEG6-CH2COOtBu;NH2-PEG6-C1-Boc;NH2CH2CH2(OCH2CH2)5OCH2CO2-t-Bu;NH2-PEG6-CH2COOtBu;NH-2-PEG6-C1-Boc,PROTAC Linkers,Inhibitor,NH2 PEG6 C1 Boc,inhibit,NH2PEG6C1Boc;H2N-PEG6-CH2COOtBu/3,6,9,12,15,18-Hexaoxaeicosanoic acid, 20-amino-, 1,1-dimethylethyl ester;3,6,9,12,15,18-Hexaoxaeicosanoic acid, 20-amino-, 1,1-dimethylethyl ester;tert-butyl 2-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]acetate | | CAS: | 297162-50-6 | | MF: | C18H37NO8 | | MW: | 395.48828 | | EINECS: | | | Product Categories: | | | Mol File: | 297162-50-6.mol |  |
| | H2N-PEG6-CH2COOtBu Chemical Properties |
| Boiling point | 463.4±40.0 °C(Predicted) | | density | 1.065±0.06 g/cm3(Predicted) | | storage temp. | Store at 0-8 °C | | pka | 8.74±0.10(Predicted) | | Appearance | colorless liquid |
| | H2N-PEG6-CH2COOtBu Usage And Synthesis |
| Uses | NH2-PEG6-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | Biological Activity | NH2-PEG6-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | | IC 50 | PEGs | | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| | H2N-PEG6-CH2COOtBu Preparation Products And Raw materials |
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