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| | N1,N1'-(1,4-phenylenebis(methylene))bis(N1-(2-aminoethyl)ethane-1,2-diamine) HCl salt Basic information |
| Product Name: | N1,N1'-(1,4-phenylenebis(methylene))bis(N1-(2-aminoethyl)ethane-1,2-diamine) HCl salt | | Synonyms: | N1,N1'-(1,4-phenylenebis(methylene))bis(N1-(2-aminoethyl)ethane-1,2-diamine) HCl salt;Benzenedimethanamine-diethylamine;1,4-Benzenedimethanamine, N1,N1,N4,N4-tetrakis(2-aminoethyl)- | | CAS: | 71277-17-3 | | MF: | C16H32N6 | | MW: | 308.47 | | EINECS: | | | Product Categories: | | | Mol File: | 71277-17-3.mol |  |
| | N1,N1'-(1,4-phenylenebis(methylene))bis(N1-(2-aminoethyl)ethane-1,2-diamine) HCl salt Chemical Properties |
| Boiling point | 425.0±40.0 °C(Predicted) | | density | 1.088±0.06 g/cm3(Predicted) | | pka | 10.12±0.10(Predicted) |
| | N1,N1'-(1,4-phenylenebis(methylene))bis(N1-(2-aminoethyl)ethane-1,2-diamine) HCl salt Usage And Synthesis |
| Description | N1,N1'-(1,4-phenylenebis(methylene))bis(N1-(2-aminoethyl)ethane-1,2-diamine) HCl salt contains four free amine groups that are able to react with carboxylic acids, activated NHS esters and other carbonyl groups. | | Uses | Benzenedimethanamine-diethylamine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | Alkyl-Chain | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | N1,N1'-(1,4-phenylenebis(methylene))bis(N1-(2-aminoethyl)ethane-1,2-diamine) HCl salt Preparation Products And Raw materials |
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