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N-(2-CHLOROETHYL)DIBENZYLAMINE HYDROCHLORIDE

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Products Intro: Product Name:N-(2-CHLOROETHYL)DIBENZYLAMINE HYDROCHLORIDE
CAS:55-43-6
Purity:0.98 Package:1KG;5KG;25KG
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Products Intro: Product Name:N-(2-Chloroethyl)dibenzylamine hydrochloride
CAS:55-43-6
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CAS:55-43-6
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Products Intro: Product Name:N-(2-CHLOROETHYL)DIBENZYLAMINE HYDROCHLORIDE
CAS:55-43-6
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Products Intro: Product Name:N-(2-Chloroethyl)Dibenzylamine Hydrochloride
CAS:55-43-6
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N-(2-CHLOROETHYL)DIBENZYLAMINE HYDROCHLORIDE manufacturers
N-(2-CHLOROETHYL)DIBENZYLAMINE HYDROCHLORIDE Basic information
Product Name:N-(2-CHLOROETHYL)DIBENZYLAMINE HYDROCHLORIDE
Synonyms:dibenzylchlorethylaminehydrochloride;Benzenemethanamine,N-(2-chloroethyl)-N-(phenylmethyl)-, hydrochloride (1:1);Dibenamine Hydrochloride N,N-Dibenzylaminoethyl Chloride Hydrochloride N,N-Dibenzyl-2-chloroethylamine Hydrochloride;N-(2-Chloroethyl)dibenzylamine Hydrochloride;DIBENAMINE HYDROCHLORIDE;dibenzyl(2-chloroethyl)ammonium chloride;n-(2-chloroethyl)-dibenzylaminhydrochloride;n-(2-chloroethyl)-n-(phenylmethyl)-benzenemethanaminhydrochloride
CAS:55-43-6
MF:C16H19Cl2N
MW:296.23
EINECS:200-234-5
Product Categories:Building Blocks;Chemical Synthesis;Nitrogen Compounds;Organic Building Blocks;Amine Salts;Amine Salts;Nitrogen Compounds;Organic Building Blocks
Mol File:55-43-6.mol
N-(2-CHLOROETHYL)DIBENZYLAMINE HYDROCHLORIDE Structure
N-(2-CHLOROETHYL)DIBENZYLAMINE HYDROCHLORIDE Chemical Properties
Melting point 190-193 °C(lit.)
Boiling point 449.72°C (rough estimate)
density 1.1507 (rough estimate)
refractive index 1.6300 (estimate)
storage temp. Inert atmosphere,Room Temperature
solubility almost transparency in Methanol
form Crystalline Powder
color White to off-white
Merck 14,2138
InChI1S/C16H18ClN.ClH/c17-11-12-18(13-15-7-3-1-4-8-15)14-16-9-5-2-6-10-16;/h1-10H,11-14H2;1H
InChIKeyLZXCEBPGNFLHEQ-UHFFFAOYSA-N
SMILESCl.ClCCN(Cc1ccccc1)Cc2ccccc2
CAS DataBase Reference55-43-6(CAS DataBase Reference)
EPA Substance Registry SystemN-(2-Chloroethyl)dibenzylamine hydrochloride (55-43-6)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-37/39
WGK Germany 3
RTECS HQ6825000
HazardClass IRRITANT
HS Code 29214900
Storage Class11 - Combustible Solids
Hazard ClassificationsEye Irrit. 2
Skin Irrit. 2
STOT SE 3
ToxicityLD50 s.c. in mice: 800 mg/kg (Nickerson, Nomaguchi)
MSDS Information
ProviderLanguage
SigmaAldrich English
N-(2-CHLOROETHYL)DIBENZYLAMINE HYDROCHLORIDE Usage And Synthesis
UsesSympatholytin was used as 5-Hydroxytryptamine antagonists in this study.Sympatholytin preferentially blocked postsynaptic alpha receptors.
General DescriptionN-(2-Chloroethyl)dibenzylamine hydrochloride is also referred as dibenamine. Mechanism of protection against carbon tetrachloride-induced hepatotoxicity produced by pretreatment with [N-(2-chloroethyl) dibenzylamine] hydrochloride has been investigated. It is a powerful adrenergic blocking agent, is known to modify the pharmacological effects of epinephrine.
in vivo

Dibenamine hydrochloride (subcutaneousinjection; 25 mg/kg; 48 and 24 hr before the administration of CCl4) decreases the CHCl3, levels at 2 and 6 hr by 30-50 percent, but did not appreciably affect the half-life of CHCl3, in the liver.Pretreatment with Dibenamine apparently slows the conversion of Ccl4 to CHCL3[1].

N-(2-CHLOROETHYL)DIBENZYLAMINE HYDROCHLORIDE Preparation Products And Raw materials
Tag:N-(2-CHLOROETHYL)DIBENZYLAMINE HYDROCHLORIDE(55-43-6) Related Product Information
N-Methylbenzylamine Dibemethine (2-CHLORO-ETHYL)-DIETHYL-AMINE N-(2-CHLOROETHYL)DIBENZYLAMINE HYDROCHLORIDE 2-Diethylaminoethylchloride hydrochloride 2-Chloroethylamine hydrochloride Dibenzylamine 2-Dimethylaminoethyl chloride hydrochloride 2-Chloroethyldimethylamine N-ethyldibenzylamine N-BENZYL-2-CHLOROETHANAMINE HYDROCHLORIDE DIBENZYLAMINE HYDROCHLORIDE N-BENZYL-N-(2-CHLOROETHYL)AMINE 2-Chloro-N-MethylethanaMine Hydrochloride N,N-dimethylbenzylamine hydrochloride 1-Dibenzylamino-2,3-dichloropropane hydrochloride Dibenamine 2-(2-METHYL-5-NITRO-1H-1-IMIDAZOLYL)ETHYL N-[2,2,2-TRICHLORO-1-(DIBENZYLAMINO)ETHYL]CARBAMATE