D-Glucosamine 6-phosphate

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D-Glucosamine 6-phosphate Basic information
Product Name:D-Glucosamine 6-phosphate
Synonyms:D-glucosamine 6-phosphate free acid;(5-amino-2,3,4-trihydroxy-6-oxo-hexoxy)phosphonic acid;2-Amino-2-deoxy-D-glucose 6-phosphoric acid;D-Glucosamine 6-Phosphate Hydrate;2-AMino-2-deoxy-D-glucose 6-(Dihydrogen Phosphate);((2R,3S,4R,5R)-5-aMino-3,4,6-trihydroxytetrahydro-2H-pyran-2-yl)Methyl dihydrogen phosphate;aldehydo-D-glucosamine 6-phosphate;2-amino-2-deoxy-D-glucopyranose 6-phosphate
CAS:3616-42-0
MF:C6H14NO8P
MW:259.15
EINECS:
Product Categories:Carbohydrate LibraryCarbohydrates;Carbohydrates;Carbohydrates A to;Carbohydrates GBiochemicals and Reagents;Metabolic Libraries;Metabolomics;Monosaccharide;Carbohydrates & Derivatives;Intermediates & Fine Chemicals;Pharmaceuticals;Phosphorylating and Phosphitylating Agents
Mol File:3616-42-0.mol
D-Glucosamine 6-phosphate Structure
D-Glucosamine 6-phosphate Chemical Properties
Melting point >127°C (dec.)
Boiling point 652.2±65.0 °C(Predicted)
density 1.749±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility Water (Slightly)
pkapKa 6.10 /8.14(H2O,t = 26.3,c=0.01,N2)(Approximate)
form Solid
color White to Off-White
biological sourcenatural (inorganic)
Water Solubility water: 50mg/mL, clear to hazy, colorless to almost colorless
Stability:Hygroscopic
InChI1S/C6H14NO8P/c7-3(1-8)5(10)6(11)4(9)2-15-16(12,13)14/h1,3-6,9-11H,2,7H2,(H2,12,13,14)
InChIKeyAEJSSXDYDSUOOZ-UHFFFAOYSA-N
SMILESNC(C=O)C(O)C(O)C(O)COP(O)(O)=O
Safety Information
WGK Germany 3
Storage Class11 - Combustible Solids
MSDS Information
ProviderLanguage
SigmaAldrich English
D-Glucosamine 6-phosphate Usage And Synthesis
UsesD-Glucosamine 6-phosphate is an endogenous metabolite that can be synthesized by glutamine fructose-6-phosphate amidotransferase (GFAT). D-Glucosamine 6-phosphate can be used for the research of diabetes mellitus[1].
DefinitionChEBI: The pyranose form of D-glucosamine 6-phosphate.
General DescriptionD-Glucosamine 6-phosphate, the natural form of glucosamine, is a monosaccharide produced during hexosamine biosynthesis pathway by the enzyme glucosamine-6-phosphate deaminase from the two substrates fructose 6-phosphate and glutamine.
References[1] Wu G, et al. Presence of glutamine:fructose-6-phosphate amidotransferase for glucosamine-6-phosphate synthesis in endothelial cells: effects of hyperglycaemia and glutamine. Diabetologia. 2001 Feb;44(2):196-202. DOI:10.1007/s001250051599
D-Glucosamine 6-phosphate Preparation Products And Raw materials
Tag:D-Glucosamine 6-phosphate(3616-42-0) Related Product Information
Glucosamine Glucosamine, D-[6-3H] 6-phosphate Acetyl-D-glucosamine, 1-phosphate-[glucosamine-6-3H] disodium salt N-Acetyl-alpha-D-glucosamine-1-phosphate disodium salt D-Glucosamine 6-phosphate sodium salt D-Glucosamine 6-phosphate N-Acetyl-alpha-D-glucosamine 6-phosphate disodium salt alpha-D-Glucosamine 1-phosphate glucosamine-1-phosphate acetyltransferase glucosamine 4-phosphate glucosamine-6-phosphate isomerase N-Acetyl-glucosamine 1-phosphate 2,3-Di(3-hydroxymyristoyl)glucosamine 1-phosphate N-Acetyl-D-Glucosamine 6-Phosphate,N-ACETYL-D-GLUCOSAMINE 6-PHOSPHATE DISODIUM SALT D-Glucosamine-6-phosphate barium salt,GLUCOSAMINE-6-PHOSPHATE BARIUM SALT