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| | 1,2-DISTEAROYL-D70-3-SN-GLYCEROPHOSPHATIDYLCHOLINE Basic information |
| Product Name: | 1,2-DISTEAROYL-D70-3-SN-GLYCEROPHOSPHATIDYLCHOLINE | | Synonyms: | 18:0 PC D70;1,2-DISTEAROYL-D70-3-SN-GLYCEROPHOSPHATIDYLCHOLINE;1,2-DISTEAROYL-D70-SN-GLYCERO-3-PHOSPHOCHOLINE;1,2-DISTEAROYL-D70-SN-GLYCERO-3-PHOSPHOCHOLINE;18:0 PC-D70;1,2-Distearoyl-d35-sn-glycero-3-PC;1,2-Distearoyl-d70-sn-glycero-3-PC | | CAS: | 56952-01-3 | | MF: | C44H88NO8P | | MW: | 790.16 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File |  |
| | 1,2-DISTEAROYL-D70-3-SN-GLYCEROPHOSPHATIDYLCHOLINE Chemical Properties |
| storage temp. | -20°C | | solubility | Ethanol: 30 mg/ml | | form | A crystalline solid | | color | White to off-white | | InChIKey | NRJAVPSFFCBXDT-MNVUKWGGSA-N |
| WGK Germany | WGK 3 | | Storage Class | 11 - Combustible Solids |
| | 1,2-DISTEAROYL-D70-3-SN-GLYCEROPHOSPHATIDYLCHOLINE Usage And Synthesis |
| Description | 1,2-Distearoyl-d70-sn-glycero-3-PC is intended for use as an internal standard for the quantification of 1,2-distearoyl-sn-glycero-3-PC by GC- or LC-MS. 1,2-Distearoyl-sn-glycero-3-PC is a phospholipid containing the saturated long-chain (18:0) fatty acid stearic acid inserted at the sn-1 and sn-2 positions. It is commonly used in the generation of micelles, liposomes, and other types of artificial membranes.1,2 | | Uses | 1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d70 is the deuterium labeled 1,2-Distearoyl-sn-glycero-3-phosphorylcholine. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (1,2-Distearoyl-sn-glycero-3-PC; DSPC) is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system[1][2]. | | References | 1. Hyrup, P., Mouritsen, O.G., and Jrgensen, K. Phospholipase A2 activity towards vesicles of DPPC and DMPC-DSPC containing small amounts of SMPC Biochim. Biophys. Acta 1515(2),133-143(2001).
2. Heberle, F.A., and Feigenson, G.W. Phase separation in lipid membranes Cold Spring Harb. Perspect. Biol. 3(4),1-13(2011). |
| | 1,2-DISTEAROYL-D70-3-SN-GLYCEROPHOSPHATIDYLCHOLINE Preparation Products And Raw materials |
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