- DSPC
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2026-04-30
- CAS:816-94-4
- Min. Order: 1kg
- Purity: 99%HPLC
- Supply Ability: 20 tons
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| | 1,2-Distearoyl-sn-glycero-3-phosphocholine Basic information |
| Product Name: | 1,2-Distearoyl-sn-glycero-3-phosphocholine | | Synonyms: | DISTEAROYL LECITHIN;L-ALPHA-PHOSPHATIDYLCHOLINE, DISTEAROYL;L-BETA,GAMMA-DISTEAROYL-ALPHA-LECITHIN;(R)-(7-lauroyl-4-oxido-10-oxo-3,5,9-trioxa-4-phosphaheptacosyl)trimethylammonium 4-oxide;L-A-PHOSPHATIDYLCHOLINE, DISTEAROYL;1,2-DISTEAROYL-SN-GLYCERO-3-PHOSPHOCHOLINE;1,2-Distearoyl-sn-glycero-3-phosphorylcholine (DSPC);L-A-PHOSPHATIDYLCHOLINE DISTEAROYL*CRYST SYNTHETIC | | CAS: | 816-94-4 | | MF: | C44H88NO8P | | MW: | 790.15 | | EINECS: | 212-440-2 | | Product Categories: | | | Mol File: | 816-94-4.mol |  |
| | 1,2-Distearoyl-sn-glycero-3-phosphocholine Chemical Properties |
| Melting point | 236°C(lit.) | | storage temp. | -20°C | | solubility | slightly sol. in Chloroform | | form | powder to crystal | | color | White to Almost white | | biological source | semisynthetic | | BRN | 3923978 | | Stability: | Stable. Incompatible with strong oxidizing agents. | | Cosmetics Ingredients Functions | SKIN CONDITIONING | | InChIKey | NRJAVPSFFCBXDT-HUESYALOSA-N | | SMILES | [C@H](OC(=O)CCCCCCCCCCCCCCCCC)(COP([O-])(=O)OCC[N+](C)(C)C)COC(=O)CCCCCCCCCCCCCCCCC |&1:0,r| |
| Safety Statements | 22-24/25 | | WGK Germany | 3 | | F | 10-21 | | HS Code | 29232000 | | Storage Class | 13 - Non Combustible Solids |
| | 1,2-Distearoyl-sn-glycero-3-phosphocholine Usage And Synthesis |
| Description | 1,2-Distearoyl-sn-glycero-3-PC (DSPC) is a phospholipid containing the saturated long-chain (18:0) stearic acid inserted at the sn-1 and sn-2 positions. It is commonly used in the generation of micelles, liposomes, and other types of artificial membranes. | | Chemical Properties | solid | | Uses | 18:0 PC (DSPC) has been used:
- in the microbubble monolayer preparation for biomolecule delivery studies into protoplasts
- in the preparation of liposomes for immobilization studies
- in the generation of porphyrin-phospholipid (PoP) liposomes for irinotecan (IRT) and doxorubicin delivery
| | Definition | ChEBI: A phosphatidylcholine 36:0 in which both phosphatidyl acyl groups are specified as stearoyl (octadecanoyl). | | General Description | 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC) is a phospholtidylcholine with alkyl chain comprising 18 carbons. It has phophatidylcholine head group and its structure is similar to 1,2-dipalmitoyl-sn-glycero-3-phosphatidylcholine (DPPC). | | Biochem/physiol Actions | 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC) is used in combination with other members of phosphatidylcholine for the generation of mixed bilayer system. It is majorly used in conventional and stealth liposome preparation for drug delivery studies. | | References | [1] PERNILLE HYRUP Kent J Ole G Mouritsen. Phospholipase A2 activity towards vesicles of DPPC and DMPC–DSPC containing small amounts of SMPC[J]. Biochimica et biophysica acta. Biomembranes, 2001, 1515 2: Pages 133-143. DOI: 10.1016/s0005-2736(01)00407-2
[2] FREDERICK A HEBERLE Gerald W F. Phase separation in lipid membranes.[J]. Cold Spring Harbor perspectives in biology, 2011, 3 4. DOI: 10.1101/cshperspect.a004630
[3] S MABREY J M S. Investigation of phase transitions of lipids and lipid mixtures by sensitivity differential scanning calorimetry.[J]. Proceedings of the National Academy of Sciences of the United States of America, 1976, 73 11: 3862-3866. DOI: 10.1073/pnas.73.11.3862 |
| | 1,2-Distearoyl-sn-glycero-3-phosphocholine Preparation Products And Raw materials |
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