2-amino-6-fluoro-N-(5-fluoro-4-(4-(4-(oxetan-3-yl)piperazine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide(WXC04788)

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2-amino-6-fluoro-N-(5-fluoro-4-(4-(4-(oxetan-3-yl)piperazine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide(WXC04788) Suppliers list
Company Name: Accela ChemBio Inc.
Tel: +1-858-6993322 +86-18019713315
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Products Intro: Product Name:2-Amino-6-fluoro-N-[5-fluoro-4-[4-[4-(3-oxetanyl)piperazine-1-carbonyl]-1-piperidyl]-3-pyridyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CAS:1613191-99-3
Purity:>98% Package:0.025g;0.05g;0.1g;0.25g Remarks:SY282745
Company Name: TargetMol Chemicals Inc.
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Email: marketing@targetmol.com
Products Intro: Product Name:Gartisertib；ATR inhibitor 2
CAS:1613191-99-3
Purity:98.00% Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: TargetMol Chemicals Inc.
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Products Intro: Product Name:Gartisertib
CAS:1613191-99-3
Package:25mg;1200USD|50mg;1570USD|100mg;2360USD
Company Name: Aladdin Scientific
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Email: tp@aladdinsci.com
Products Intro: Product Name:VX-803 (M4344)
CAS:1613191-99-3
Purity:98% Package:$385.9/5mg;$642.9/10mg;$1286.9/25mg;Bulk package Remarks:98%
Company Name: TargetMol Chemicals Inc.
Tel: 13564774135
Email: marketing@targetmol.com
Products Intro: Product Name:Gartisertib
CAS:1613191-99-3
Purity:99.52% Package:25mg;1070USD|50mg;1570USD|100mg;2360USD

2-amino-6-fluoro-N-(5-fluoro-4-(4-(4-(oxetan-3-yl)piperazine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide(WXC04788) manufacturers

  • Gartisertib
  • Gartisertib pictures
  • $1070.00
  • 2026-07-14
  • CAS:1613191-99-3
  • Purity: 99.52%
  • Supply Ability: 10g
  • Gartisertib
  • Gartisertib pictures
  • $1130.00
  • 2025-05-29
  • CAS:1613191-99-3
  • Purity: 99.52%
  • Supply Ability: 10g
2-amino-6-fluoro-N-(5-fluoro-4-(4-(4-(oxetan-3-yl)piperazine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide(WXC04788) Basic information
Product Name:2-amino-6-fluoro-N-(5-fluoro-4-(4-(4-(oxetan-3-yl)piperazine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide(WXC04788)
Synonyms:2-amino-6-fluoro-N-(5-fluoro-4-(4-(4-(oxetan-3-yl)piperazine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide(WXC04788);2-amino-6-fluoro-N-(5-fluoro-4-(4-(4-(oxetan-3-yl)piperazine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;M-4344;ATR inhibitor 2;Pyrazolo[1,5-a]pyrimidine-3-carboxamide, 2-amino-6-fluoro-N-[5-fluoro-4-[4-[[4-(3-oxetanyl)-1-piperazinyl]carbonyl]-1-piperidinyl]-3-pyridinyl]-;2-Amino-6-fluoro-N-[5-fluoro-4-[4-[4-(3-oxetanyl)piperazine-1-carbonyl]-1-piperidyl]-3-pyridyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;VX-803(M4344 );MSC-2580591A
CAS:1613191-99-3
MF:C25H29F2N9O3
MW:541.55
EINECS:
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Mol File:1613191-99-3.mol
2-amino-6-fluoro-N-(5-fluoro-4-(4-(4-(oxetan-3-yl)piperazine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide(WXC04788) Structure
2-amino-6-fluoro-N-(5-fluoro-4-(4-(4-(oxetan-3-yl)piperazine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide(WXC04788) Chemical Properties
density 1+-.0.1 g/cm3(Predicted)
form Solid
pka4.89±0.46(Predicted)
color Light yellow to yellow
Safety Information
MSDS Information
2-amino-6-fluoro-N-(5-fluoro-4-(4-(4-(oxetan-3-yl)piperazine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide(WXC04788) Usage And Synthesis
Uses2-Amino-6-fluoro-N-[5-fluoro-4-[4-[[4-(oxetan-3-yl)piperazin-1-yl]carbonyl]-1-piperidyl]-3-pyridyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide is an ATP-competitive and selective ATR inhibitor. Exhibits antitumor activity. Useful for monotherapy.
in vivo

In monotherapy efficacy studies Gartisertib shows tumor stasis to regression in tumor models with alternative lengthening of telomeres (ALT). In combination with PARP inhibitors, tumor regression could be observed in triple-negative breast cancer xenograft models[1].

IC 50ATR: <150 pM (Ki)
Tag:2-amino-6-fluoro-N-(5-fluoro-4-(4-(4-(oxetan-3-yl)piperazine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide(WXC04788)(1613191-99-3) Related Product Information
2-amino-6-fluoro-N-(5-fluoro-4-(4-(4-(oxetan-3-yl)piperazine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide(WXC04788)