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Dihydroergocristine mesylate

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Dihydroergocristine mesylate manufacturers

Dihydroergocristine mesylate Basic information
Product Name:Dihydroergocristine mesylate
Synonyms:(5’-alpha,10-alpha)-nylmethyl)monomethanesulfonate(salt);(5'alpha, 10alpha)-9,10-Dihydro-12'-hydroxy-2'-(1-methylethyl)-5'-(phenylmethyl)-ergotaman-3',6',18-trione mesylate;C13168;(5'α,10α)-9,10-Dihydro-12'-hydroxy-2'-(1-methylethyl)-5'-(phenylmethyl)-ergotaman-3',6',18-trionemesylate;9,10-dihydro-ergocristinmonomethanesulfonate(salt);dihydroergocristinmesilat;ergotamane-3’,6’,18-trione,9,10-dihydro-12’-hydroxy-2’-(1-methylethyl)-5’-(phe;5'alpha-benzyl-9,10alpha-dihydro-12'-hydroxy-2'-isopropylergotaman-3',6',18-trione monomethanesulphonate
CAS:24730-10-7
MF:C35H41N5O5.CH4O3S
MW:707.84
EINECS:246-434-6
Product Categories:Organics;DID - DINDrugs of Abuse;ErgotamineForensic and Veterinary Standards;AlkaloidsAlphabetic;Chemical Structure;D;Drugs of Abuse;Drugs&Metabolites;Neat Compounds;Serotonin receptor
Mol File:24730-10-7.mol
Dihydroergocristine mesylate Structure
Dihydroergocristine mesylate Chemical Properties
Melting point 210 °C
storage temp. Store at RT
solubility H2O: 10 mg/mL
form Solid
color White to off-white
InChIKeySPXACGZWWVIDGR-NKQTVNRENA-N
Safety Information
RIDADR UN 1544 6.1/PG 2
WGK Germany 2
RTECS KE7600000
HazardClass 6.1(b)
PackingGroup III
HS Code 29396900
MSDS Information
ProviderLanguage
SigmaAldrich English
Dihydroergocristine mesylate Usage And Synthesis
Chemical PropertiesWhite or almost white, fine crystalline powder.
Uses5-HT receptor antagonist; partial agonist at adrenergic and dopaminergic receptors
UsesAlpha receptor blocking
Uses4,10-Dihydroergocristine Methanesulfonate is an nontoxic and well tolerated drug that exerts agonistic and antagonistic activity on dopaminergic and adrenergic receptors. 4,10-Dihydroergocristine Meth anesulfonate is known to exhibit protective properties to the brain against metabolic effects of ischemia by acting at a cellular level.
DefinitionChEBI: The methanesulfonic acid salt of dihydroergocristine. It has been used as the for the symptomatic treatment of mental deterioration associated with cerebrovascular insufficiency and in peripheral vascular disease. It is also a component of ergoloid mesylat (codergocrine mesilate), a mixture of ergot alkaloid derivatives that is used as a vasodilator and has shown mild benefits in the treatment of vascular dementia.
Biological Activity5-HT receptor antagonist; partial agonist at adrenergic and dopaminergic receptors.
storageRoom temperature
Dihydroergocristine mesylate Preparation Products And Raw materials
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