(RS)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxybenzyl)pyrimidine-2,4-dione

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(RS)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxybenzyl)pyrimidine-2,4-dione manufacturers

  • UBP 296
  • UBP 296 pictures
  • $987.00
  • 2026-05-11
  • CAS:745055-86-1
  • Purity:
  • Supply Ability: 10g
(RS)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxybenzyl)pyrimidine-2,4-dione Basic information
Product Name:(RS)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxybenzyl)pyrimidine-2,4-dione
Synonyms:UBP 296;1(2H)-Pyrimidinepropanoic acid, α-amino-3-[(2-carboxyphenyl)methyl]-3,4-dihydro-2,4-dioxo-;(RS)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxybenzyl)pyrimidine-2,4-dione
CAS:745055-86-1
MF:C15H15N3O6
MW:333.3
EINECS:
Product Categories:Glutamate receptor
Mol File:Mol File
(RS)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxybenzyl)pyrimidine-2,4-dione Structure
(RS)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxybenzyl)pyrimidine-2,4-dione Chemical Properties
Melting point 190.8-191.2 °C (decomp)(Solv: water (7732-18-5))
Boiling point 603.0±65.0 °C(Predicted)
density 1.525±0.06 g/cm3(Predicted)
storage temp. Store at RT
solubility <3.33mg/ml in 1eq. NaOH; <3.33mg/ml in DMSO
pka2.12±0.10(Predicted)
Safety Information
MSDS Information
(RS)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxybenzyl)pyrimidine-2,4-dione Usage And Synthesis
UsesUBP 296 is a novel, potent and selective kainate receptor antagonist.
DefinitionChEBI: 2-[[3-(2-amino-2-carboxyethyl)-2,6-dioxo-1-pyrimidinyl]methyl]benzoic acid is an alpha-amino acid.
Biological ActivitySelective and potent GluR5-subunit containing kainate receptor antagonist (apparent K D = 1.09 mM). Displays ~ 90-fold selectivity over AMPA receptors and recombinant human GluR6- and KA2-containing kainate receptors. Has little or no action at NMDA or group I mGlu receptors. Selectively blocks kainate receptor-mediated LTP induction in rat hippocampal mossy fibres.
storageStore at RT
(RS)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxybenzyl)pyrimidine-2,4-dione Preparation Products And Raw materials
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