| Company Name: |
Chengdu Feibo Pharm Technology Co., Ltd
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| Tel: |
+86 028-84641798 15982321820 |
| Email: |
abby@arkpharm.com |
| Products Intro: |
Product Name:2-ENEVALPROIC ACID
CAS:60218-41-9
Purity:95%+ Package:5g;50g;100g;250g;500g;1kg;5kg
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| Company Name: |
J & K SCIENTIFIC LTD.
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| Tel: |
18210857532; 18210857532 |
| Email: |
jkinfo@jkchemical.com |
| Products Intro: |
Product Name:(E,Z) 2-Propyl-2-pentenoic Acid
CAS:60218-41-9
Package:100Mg,10Mg
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2-ENEVALPROIC ACID manufacturers
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| | 2-ENEVALPROIC ACID Basic information |
| | 2-ENEVALPROIC ACID Chemical Properties |
| Melting point | 36 °C | | Boiling point | 242.9±9.0 °C(Predicted) | | density | 0.956±0.06 g/cm3(Predicted) | | storage temp. | Hygroscopic, -20°C Freezer, Under Inert Atmosphere | | solubility | DMF: 15 mg/ml; DMSO: 20 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 1 mg/ml | | pka | 5.03±0.36(Predicted) | | BRN | 1721109 | | Stability: | Hygroscopic, Light, Temperature and Moisture Sensitive | | Major Application | pharmaceutical | | InChI | 1S/C8H14O2/c1-3-5-7(6-4-2)8(9)10/h5H,3-4,6H2,1-2H3,(H,9,10)/b7-5+ | | InChIKey | ZKNJEOBYOLUGKJ-FNORWQNLSA-N | | SMILES | CC/C=C(CCC)/C(O)=O |
| Hazard Codes | T | | Risk Statements | 25 | | Safety Statements | 45 | | RIDADR | UN 2811 6.1 / PGIII | | WGK Germany | 3 | | Storage Class | 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | | Hazard Classifications | Acute Tox. 3 Oral |
| | 2-ENEVALPROIC ACID Usage And Synthesis |
| Description | (E,Z)-2-propyl-2-Pentenoic acid is a bioactive metabolite of valproic acid that exhibits the same profile and potency of anticonvulsant activity in animal models as its parent compound without any observed teratogenicity and hepatotoxicity. | | Chemical Properties | Light-Yellow Solid | | Uses | A metabolite of Valproic Acid | | References | [1] A W RETTENMEIER. Metabolic fate of valproic acid in the rhesus monkey. Formation of a toxic metabolite, 2-n-propyl-4-pentenoic acid.[J]. Drug Metabolism and Disposition, 1986, 14 4: 443-453.
[2] WOLFGANG LSCHER. Trans-2-en-valproate: reevaluation of its anticonvulsant efficacy in standardized seizure models in mice, rats and dogs[J]. Epilepsy Research, 1991, 9 3: Pages 195-210. DOI: 10.1016/0920-1211(91)90053-i |
| | 2-ENEVALPROIC ACID Preparation Products And Raw materials |
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