| Company Name: |
J & K SCIENTIFIC LTD.
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| Tel: |
18210857532; 18210857532 |
| Email: |
jkinfo@jkchemical.com |
| Products Intro: |
Product Name:(+/-)-2-Propyl-4-pentenoic Acid
CAS:1575-72-0
Package:100Mg,1g
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| Company Name: |
Clearsynth Labs Limited
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| Tel: |
+91-22-26355700 |
| Email: |
info@clearsynth.com |
| Products Intro: |
Product Name:(+/-)-2-Propyl-4-pentenoic Acid
CAS:1575-72-0
Remarks:CS-T-15512
|
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| | 2-PROPYL-4-PENTENOIC ACID Basic information |
| | 2-PROPYL-4-PENTENOIC ACID Chemical Properties |
| Boiling point | 95-100 °C(Press: 5 Torr) | | density | 0.943±0.06 g/cm3(Predicted) | | storage temp. | Refrigerator | | solubility | Methanol: Slightly Soluble | | form | An oil | | pka | 4.70±0.20(Predicted) | | color | Colorless to light yellow | | Stability: | Toxic |
| Toxicity | LD50 intraperitoneal in mouse: 1160mg/kg |
| | 2-PROPYL-4-PENTENOIC ACID Usage And Synthesis |
| Description | (±)-2-propyl-4-Pentenoic acid (4-ene VPA) is a major metabolite of valproic acid . It undergoes β-oxidation to form reactive metabolites that induce hepatotoxicity in rats. 4-ene VPA is also neuroteratogenic, reducing forebrain size and inducing deformation of the neural tube in mouse embryos. | | Chemical Properties | Clear Colorless Oil | | Uses | A metabolite of Valproic Acid | | Definition | ChEBI: 2-n-Propyl-4-pentenoic acid is a methyl-branched fatty acid. | | Hazard | Moderately toxic. | | References | [1] W TANG F S A. A comparative investigation of 2-propyl-4-pentenoic acid (4-ene VPA) and its alpha-fluorinated analogue: phase II metabolism and pharmacokinetics.[J]. Drug Metabolism and Disposition, 1997, 25 2: 219-227.
[2] F. GOFFLOT . In vitro neuroteratogenicity of valproic acid and 4-en-VPA[J]. Neurotoxicology and teratology, 1995, 17 4: Pages 425-435. DOI: 10.1016/0892-0362(94)00094-t |
| | 2-PROPYL-4-PENTENOIC ACID Preparation Products And Raw materials |
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