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| | 17(R)-Resolvin D4 Basic information |
| Product Name: | 17(R)-Resolvin D4 | | Synonyms: | 17(R)-Resolvin D4;6,8,10,13,15,19-Docosahexaenoic acid, 4,5,17-trihydroxy-, (4S,5R,6E,8E,10Z,13Z,15E,17R,19Z)- | | CAS: | 528583-89-3 | | MF: | C22H32O5 | | MW: | 376.49 | | EINECS: | | | Product Categories: | | | Mol File: | 528583-89-3.mol |  |
| | 17(R)-Resolvin D4 Chemical Properties |
| Boiling point | 609.2±55.0 °C(Predicted) | | density | 1.101±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: 50 mg/ml; DMSO: unstable; Ethanol: 50 mg/ml; PBS (pH 7.2): 0.5 mg/ml | | pka | 4.50±0.10(Predicted) |
| | 17(R)-Resolvin D4 Usage And Synthesis |
| Description | 17(R)-Resolvin D4 (17(R)-RvD4) is an aspirin-triggered epimer of RvD4 .1 | | Uses | 17(R)-Resolvin D4 (17(R)-RvD4) is the R-enantiomer of Resolvin D4. Resolvin D4 (RvD4), a specialized proresolving mediator, can be produced in bioactive levels during S. aureus infection[1]. | | Definition | ChEBI: Aspirin-triggered resolvin D4 is a member of the class of resolvins that is (6E,8E,10Z,13Z,15E,19Z)-docosahexaenoic acid carrying three hydroxy substituents at positions 4, 5 and 17 (the 4S,5R,17R-stereoisomer). It has a role as an anti-inflammatory agent, a human xenobiotic metabolite and a mouse metabolite. It is a resolvin, a secondary allylic alcohol, a triol and a hydroxy polyunsaturated fatty acid. | | References | 1. Serhan, C.N., Hong, S., Gronert, K., et al. Resolvins: A family of bioactive products of ω-3 fatty acid transformation circuits by aspirin treatment that counter proinflammation signals J. Exp. Med. 196(8),1025-1037(2002). |
| | 17(R)-Resolvin D4 Preparation Products And Raw materials |
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