|
|
| | Lin28-IN-1 Basic information |
| Product Name: | Lin28-IN-1 | | Synonyms: | Lin28-IN-1;Lin28-let-7a antagonist 1;1-Piperazinecarboxylic acid, 4-[1-(4-carboxyphenyl)-1,4-dihydro-4,4-dimethyl-8-nitro[1]benzopyrano[4,3-c]pyrazol-7-yl]-, 1-(phenylmethyl) ester;4-(7-(4-((Benzyloxy)carbonyl)piperazin-1-yl)-4,4-dimethyl-8-nitrochromeno[4,3-c]pyrazol-1(4H)-yl)benzoic acid;Inhibitor,inhibit,MicroRNA,Lin-28-let-7a antagonist 1,Lin28 let 7a antagonist 1,miRNA,Lin28let7a antagonist 1;Lin28-let-7a antagonist 1, 10 mM in DMSO | | CAS: | 2024548-03-4 | | MF: | C31H29N5O7 | | MW: | 583.59 | | EINECS: | | | Product Categories: | | | Mol File: | 2024548-03-4.mol |  |
| | Lin28-IN-1 Chemical Properties |
| Boiling point | 813.8±65.0 °C(Predicted) | | density | 1.42±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | pka | 3.72±0.10(Predicted) | | form | Solid | | color | Light yellow to yellow |
| | Lin28-IN-1 Usage And Synthesis |
| Uses | Lin28-let-7a antagonist 1 shows a clear antagonistic effect against the Lin28-let-7a interaction with an IC50 of 4.03 μM for Lin28A-let-7a-1 interaction. | | References | [1] Lim D, et al. Discovery of a Small-Molecule Inhibitor of Protein-MicroRNA Interaction Using Binding Assay with a Site-Specifically Labeled Lin28. J Am Chem Soc. 2016 Oct 7. DOI:10.1021/jacs.6b06965 |
| | Lin28-IN-1 Preparation Products And Raw materials |
|