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| | 2-METHYL-5-HYDROXYTRYPTAMINE Basic information |
| Product Name: | 2-METHYL-5-HYDROXYTRYPTAMINE | | Synonyms: | Methylserotonin;3-(2-Aminopropyl)-1H-indol-5-ol;5-Hydroxy-α-methyl-1H-indole-3-ethanamine;α-CH3-5-HT;α-Methyl-5-HT;1H-Indol-5-ol, 3-(2-aminoethyl)-2-methyl-;1H-Indol-5-ol,3-(2-aMinoethyl)-2-Methyl-(NP3308);2-Methylserotonin Hydrochloride | | CAS: | 78263-90-8 | | MF: | C11H14N2O | | MW: | 190.24 | | EINECS: | | | Product Categories: | Serotonin receptor | | Mol File: | 78263-90-8.mol |  |
| | 2-METHYL-5-HYDROXYTRYPTAMINE Chemical Properties |
| Boiling point | 420.9±40.0 °C(Predicted) | | density | 1.242±0.06 g/cm3(Predicted) | | RTECS | NM2565000 | | storage temp. | Keep in dark place,Inert atmosphere,2-8°C | | solubility | H2O: 4.5 mg/mL | | form | solid | | pka | 10.17±0.40(Predicted) | | color | tan |
| | 2-METHYL-5-HYDROXYTRYPTAMINE Usage And Synthesis |
| Uses | 2-Methylserotonin is a tryptamine derivative closely related to the neurotransmitter serotonin (S274980) which is a monoamine neurotransmitter, and acts as a moderately selective full agonist at the 5-HT3 receptor. | | Definition | ChEBI: 2-methylserotonin is a member of tryptamines. It has a role as a serotonergic agonist. It is functionally related to a serotonin. | | in vivo | 2-Methyl-5-HT (2-Methyl-5-hydroxytryptamine) significantly decreases time of immobility thus showing anti-depressive-like effects[1]. | Animal Model: | Male Sprague-Dawley rats[1] | | Dosage: | 3 mg/kg | | Administration: | I.p.; 45 minutes | | Result: | Significantly decreased time of immobility thus showing anti-depressive-like effects.
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| | IC 50 | 5-HT3 Receptor |
| | 2-METHYL-5-HYDROXYTRYPTAMINE Preparation Products And Raw materials |
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