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| | SGLT inhibitor-1 Basic information |
| Product Name: | SGLT inhibitor-1 | | Synonyms: | SGLT inhibitor-1;D-Glucitol, 1,5-anhydro-4-deoxy-1-C-[7-[(2,3-dihydro-1,4-benzodioxin-6-yl)methyl]-2,3-dihydro-4-methoxy-5-benzofuranyl]-4-fluoro-, (1S)-;SGLT inhibitor 1,SGLT inhibitor1 | | CAS: | 2247314-23-2 | | MF: | C24H27FO8 | | MW: | 462.47 | | EINECS: | | | Product Categories: | | | Mol File: | 2247314-23-2.mol |  |
| | SGLT inhibitor-1 Chemical Properties |
| Boiling point | 667.5±55.0 °C(Predicted) | | density | 1.45±0.1 g/cm3(Predicted) | | pka | 12.62±0.70(Predicted) |
| | SGLT inhibitor-1 Usage And Synthesis |
| Uses | SGLT inhibitor-1 is a potent dual inhibitor of sodium glucose co-transporter proteins (SGLTs), inhibits hSGLT1 and hSGLT2 with IC50s of 43 nM and 9 nM, respectively[1]. | | References | [1] Xu G, et al. Design, synthesis and biological evaluation of (2S,3R,4R,5S,6R)-5-fluoro-6-(hydroxymethyl)-2-aryltetrahydro-2H-pyran-3,4-diols as potent and orally active SGLT dual inhibitors. Bioorg Med Chem Lett. 2018 Nov 15;28(21):3446-3453. DOI:10.1016/j.bmcl.2018.09.025 |
| | SGLT inhibitor-1 Preparation Products And Raw materials |
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