2'-Deoxyadenosine-5'-O-monophosphorothioate sodium salt

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2'-Deoxyadenosine-5'-O-monophosphorothioate sodium salt Basic information
Product Name:2'-Deoxyadenosine-5'-O-monophosphorothioate sodium salt
Synonyms:2’-deoxyadenosine-5’-monophosphorothioate(5’-damps),sodiumsalt;5'-DAMPS SODIUM SALT;2''-Deoxyadenosine 5''-phosphorothioic acid;Adenosine, 2'-deoxy-, 5'-(dihydrogen phosphorothioate);2'-Deoxyadenosine 5'-O-thiophosphate sodium salt;O-(((2R,3S,5R)-5-(6-Amino-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl) O,S-dihydrogen phosphorothioate;5′,-dAMPS;2'-Deoxyadenosine-5'-O-monophosphorothioate sodium salt
CAS:64145-26-2
MF:C10H14N5O5PS
MW:347.29
EINECS:
Product Categories:
Mol File:64145-26-2.mol
2'-Deoxyadenosine-5'-O-monophosphorothioate sodium salt Structure
2'-Deoxyadenosine-5'-O-monophosphorothioate sodium salt Chemical Properties
Boiling point 698.2±65.0 °C(Predicted)
density 2.12±0.1 g/cm3(Predicted)
pka1.11±0.50(Predicted)
Safety Information
MSDS Information
2'-Deoxyadenosine-5'-O-monophosphorothioate sodium salt Usage And Synthesis
Uses5'-dAMPS is an analogue of 5'-dAMP and thus a potential substrate, competitive inhibitor or regulator of enzymes that interact with dAMP[1].
References[1] Koziolkiewicz M, et al. The mononucleotide-dependent, nonantisense mechanism of action of phosphodiester and phosphorothioate oligonucleotides depends upon the activity of an ecto-5'-nucleotidase. Blood. 2001 Aug 15;98(4):995-1002. DOI:10.1182/blood.v98.4.995
2'-Deoxyadenosine-5'-O-monophosphorothioate sodium salt Preparation Products And Raw materials
Preparation Products2'-Deoxyadenosine 5'-phosphate
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