O-乙醯絲胺酸
| 中文名称 | O-乙醯絲胺酸 |
|---|---|
| 中文同义词 | O-乙醯絲胺酸;O-乙酰-L-丝氨酸, >98%;O-乙酰基-L-丝氨酸 |
| 英文名称 | O-Acetyl-L-serine |
| 英文同义词 | (2S)-2-[[3-hydroxy-2-methyl-5-(phosphonooxymethyl)pyridin-4-yl]methylamino]-4-methylsulfanyl-butanoic acid;C00979;L-Serine, O-acetyl-;(2S)-3-(acetyloxy)-2-aminopropanoic acid;O-Acetylserine, >98%;(S)-3-Acetoxy-2-aminopropanoic acid;O-ACETYL-L-SERINE USP/EP/BP;O Acetylserine,O-Acetylserine,Endogenous Metabolite,inhibit,OAcetylserine,Inhibitor |
| CAS号 | 5147-00-2 |
| 分子式 | C5H9NO4 |
| 分子量 | 147.13 |
| EINECS号 | |
| 相关类别 | 天然氨基酸极其衍生物 |
| Mol文件 | 5147-00-2.mol |
| 结构式 |  |
O-乙醯絲胺酸 性质
| 熔点 | 151.5-151.8 °C |
|---|---|
| 沸点 | 297.7±35.0 °C(Predicted) |
| 密度 | 1.299±0.06 g/cm3(Predicted) |
| 储存条件 | 2-8°C |
| 溶解度 | 酸水溶液（少量，超声处理）、甲醇（非常少量）、水（少量溶解） |
| 形态 | 固体 |
| 酸度系数(pKa) | 1.98±0.10(Predicted) |
| 颜色 | 白色至类白色 |
| InChI | InChI=1S/C5H9NO4/c1-3(7)10-2-4(6)5(8)9/h4H,2,6H2,1H3,(H,8,9)/t4-/m0/s1 |
| InChIKey | VZXPDPZARILFQX-BYPYZUCNSA-N |
| SMILES | C(O)(=O)[C@H](COC(C)=O)N |
O-Acetylserine是细菌和植物中半胱氨酸生物合成的中间物。
|
Human Endogenous Metabolite
|
O-acetylserine (OAS) is a central metabolite of sulfur assimilation, providing the carbon backbone for synthesis of cysteine. Sulfide generated through sulfate reduction is incorporated into OAS to form cysteine. OAS displays a signalling function leading to changes in transcript levels of a specific gene set irrespective of the sulfur status of the plant. Treatment with external OAS increases sulfate transporter and adenosine 5′-phosphosulfate reductase gene expression consistent with a model of transcriptional induction by OAS.
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