4-(Trifluoromethyl)phenacyl bromide manufacturers
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| | 4-(Trifluoromethyl)phenacyl bromide Basic information |
| Product Name: | 4-(Trifluoromethyl)phenacyl bromide | | Synonyms: | 2-broMo-1-(4-(trifluoroMethyl)phenyl)ethanone;BUTTPARK 35\01-55;2-Bromo-4'-(trifluoromethyl)acetophenone, 2-Bromo-1-[4-(trifluoromethyl)phenyl]ethan-1-one;4'-(TRIFLUOROMETHYL)PHENACYL BROMIDE;4-TRIFLUOROMETHYLPHENACYL BROMIDE;2-BROMO-1-[4-(TRIFLUOROMETHYL)PHENYL]-1-ETHANONE;2-BROMO-1-[4-(TRIFLUOROMETHYL)PHENYL]ETHAN-1-ONE;2-Bromo-1-[4-(trifluoromethyl)phenyl]ethan-1-one, tech | | CAS: | 383-53-9 | | MF: | C9H6BrF3O | | MW: | 267.04 | | EINECS: | 609-544-9 | | Product Categories: | Benzene series | | Mol File: | 383-53-9.mol |  |
| | 4-(Trifluoromethyl)phenacyl bromide Chemical Properties |
| Melting point | 45 °C | | Boiling point | 264.2±40.0 °C(Predicted) | | density | 1.592±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | soluble in Methanol | | form | powder to crystal | | color | White to Yellow to Orange | | InChI | 1S/C9H6BrF3O/c10-5-8(14)6-1-3-7(4-2-6)9(11,12)13/h1-4H,5H2 | | InChIKey | HEMROKPXTCOASZ-UHFFFAOYSA-N | | SMILES | FC(F)(F)c1ccc(cc1)C(=O)CBr | | CAS DataBase Reference | 383-53-9(CAS DataBase Reference) |
| Hazard Codes | C,Xi | | Risk Statements | 34-36/37/38 | | Safety Statements | 26-36/37/39-45-36 | | RIDADR | 1759 | | WGK Germany | 3 | | HazardClass | CORROSIVE | | PackingGroup | III | | HS Code | 29147000 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | 4-(Trifluoromethyl)phenacyl bromide Usage And Synthesis |
| Chemical Properties | White powder or crystal | | Synthesis | General procedure for the synthesis of 2-bromo-4'-(trifluoromethyl)acetophenone using 1-(bromoethynyl)-4-(trifluoromethyl)benzene as starting material: a mixed solution of haloalkynes (0.5 mmol), silver fluoride (5 mol%), and water (1 eq.) in trifluoroacetic acid (1 mL) was stirred for 6 hours at 40 °C. Upon completion of the reaction, the trifluoroacetic acid was recovered by distillation for reuse. The residue was purified by column chromatographic separation to afford the target product 2-bromo-4'-(trifluoromethyl)acetophenone. | | References | [1] Tetrahedron Letters, 2014, vol. 55, # 7, p. 1373 - 1375
[2] European Journal of Organic Chemistry, 2016, vol. 2016, # 1, p. 116 - 121
[3] Tetrahedron, 2016, vol. 72, # 27-28, p. 3818 - 3822
[4] Tetrahedron Letters, 2016, vol. 57, # 45, p. 4983 - 4986
[5] Chinese Journal of Chemistry, 2016, vol. 34, # 12, p. 1251 - 1254 |
| | 4-(Trifluoromethyl)phenacyl bromide Preparation Products And Raw materials |
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