| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:RX 67668
CAS:40709-76-0
Package:50mg/RMB 13800;25mg/RMB 10600;100mg/RMB 17500
|
RX 67668 manufacturers
- RX 67668
-
- $1980.00 / 50mg
-
2026-05-11
- CAS:40709-76-0
- Min. Order:
- Purity:
- Supply Ability: 10g
|
| | RX 67668 Basic information |
| | RX 67668 Chemical Properties |
| | RX 67668 Usage And Synthesis |
| Uses | RX 67668 is a potent cholinesterase inhibitor with an IC50 of 5 μM for both acetylcholinesterase (AChE) and butyrylcholinesterase. RX 67668 can reverse the neuromuscular blockade induced by D-tubocurarine. RX 67668 is a muscle relaxant used to relieve skeletal muscle fatigue[1][2]. | | in vivo | RX 67668 (1-4 mg/kg; i.p.) reduces by half the dose of methacholine necessary to produce red tears, whilst RX 67668 (7-2 mg/kg s.c.) is necessary to reduce the pupil diameter of the mouse to 50% of the control value[1].
Rat anterior tibialis preparation of the cat tibialis preparation demonstrates that RX 67668 (0.3-1.0 mg/kg; i.v.) is effective in reversing tubocurarine-induced muscle blockade[1].
| | References | [1] Doxey JC, et al. Some pharmacological properties of RX 67668--a new anticholinesterase. Br J Pharmacol. 1972 Nov;46(3):568P-569P. PMID:4656643
[2] Metcalf G, wt al. Evaluation of RX 72601 as an anti-curare agent. Br J Anaesth. 1975 Apr;47(4):451-6. DOI:10.1093/bja/47.4.451 |
| | RX 67668 Preparation Products And Raw materials |
|