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Pyrano[2,3-e]isoindole-8(2H)-pentanoic acid, 2-[(3E)-4,8-dimethyl-3,7-nonadien-1-yl]-α-[(2S,3S)-2-[(3E)-4,8-dimethyl-3,7-nonadien-1-yl]-3,4,7,9-tetrahydro-3,5-dihydroxy-2-methyl-7-oxopyrano[2,3-e]isoindol-8(2H)-yl]-3,4,7,9-tetrahydro-3,5-dihydroxy-2-methyl-7-oxo-, (αS,2S,3S)- Suppliers list
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Pyrano[2,3-e]isoindole-8(2H)-pentanoic acid, 2-[(3E)-4,8-dimethyl-3,7-nonadien-1-yl]-α-[(2S,3S)-2-[(3E)-4,8-dimethyl-3,7-nonadien-1-yl]-3,4,7,9-tetrahydro-3,5-dihydroxy-2-methyl-7-oxopyrano[2,3-e]isoindol-8(2H)-yl]-3,4,7,9-tetrahydro-3,5-dihydroxy-2-methyl-7-oxo-, (αS,2S,3S)- manufacturers
- Orniplabin
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2026-07-15
- CAS:733805-92-0
- Purity:
- Supply Ability: 10g
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| | Pyrano[2,3-e]isoindole-8(2H)-pentanoic acid, 2-[(3E)-4,8-dimethyl-3,7-nonadien-1-yl]-α-[(2S,3S)-2-[(3E)-4,8-dimethyl-3,7-nonadien-1-yl]-3,4,7,9-tetrahydro-3,5-dihydroxy-2-methyl-7-oxopyrano[2,3-e]isoindol-8(2H)-yl]-3,4,7,9-tetrahydro-3,5-dihydroxy-2-methyl-7-oxo-, (αS,2S,3S)- Basic information |
| Product Name: | Pyrano[2,3-e]isoindole-8(2H)-pentanoic acid, 2-[(3E)-4,8-dimethyl-3,7-nonadien-1-yl]-α-[(2S,3S)-2-[(3E)-4,8-dimethyl-3,7-nonadien-1-yl]-3,4,7,9-tetrahydro-3,5-dihydroxy-2-methyl-7-oxopyrano[2,3-e]isoindol-8(2H)-yl]-3,4,7,9-tetrahydro-3,5-dihydroxy-2-methyl-7-oxo-, (αS,2S,3S)- | | Synonyms: | Pyrano[2,3-e]isoindole-8(2H)-pentanoic acid, 2-[(3E)-4,8-dimethyl-3,7-nonadien-1-yl]-α-[(2S,3S)-2-[(3E)-4,8-dimethyl-3,7-nonadien-1-yl]-3,4,7,9-tetrahydro-3,5-dihydroxy-2-methyl-7-oxopyrano[2,3-e]isoindol-8(2H)-yl]-3,4,7,9-tetrahydro-3,5-dihydroxy-2-methyl-7-oxo-, (αS,2S,3S)-;Orniplabin | | CAS: | 733805-92-0 | | MF: | C51 H68 N2 O10 | | MW: | 869.09 | | EINECS: | | | Product Categories: | | | Mol File: | 733805-92-0.mol | ![Pyrano[2,3-e]isoindole-8(2H)-pentanoic acid, 2-[(3E)-4,8-dimethyl-3,7-nonadien-1-yl]-α-[(2S,3S)-2-[(3E)-4,8-dimethyl-3,7-nonadien-1-yl]-3,4,7,9-tetrahydro-3,5-dihydroxy-2-methyl-7-oxopyrano[2,3-e]isoindol-8(2H)-yl]-3,4,7,9-tetrahydro-3,5-dihydroxy-2-methyl-7-oxo-, (αS,2S,3S)- Structure](CAS/20210305/GIF/733805-92-0.gif) |
| | Pyrano[2,3-e]isoindole-8(2H)-pentanoic acid, 2-[(3E)-4,8-dimethyl-3,7-nonadien-1-yl]-α-[(2S,3S)-2-[(3E)-4,8-dimethyl-3,7-nonadien-1-yl]-3,4,7,9-tetrahydro-3,5-dihydroxy-2-methyl-7-oxopyrano[2,3-e]isoindol-8(2H)-yl]-3,4,7,9-tetrahydro-3,5-dihydroxy-2-methyl-7-oxo-, (αS,2S,3S)- Chemical Properties |
| Boiling point | 1017.5±65.0 °C(Predicted) | | density | 1.211±0.06 g/cm3(Predicted) | | pka | 3.46±0.21(Predicted) | | form | Solid | | color | White to off-white |
| | Pyrano[2,3-e]isoindole-8(2H)-pentanoic acid, 2-[(3E)-4,8-dimethyl-3,7-nonadien-1-yl]-α-[(2S,3S)-2-[(3E)-4,8-dimethyl-3,7-nonadien-1-yl]-3,4,7,9-tetrahydro-3,5-dihydroxy-2-methyl-7-oxopyrano[2,3-e]isoindol-8(2H)-yl]-3,4,7,9-tetrahydro-3,5-dihydroxy-2-methyl-7-oxo-, (αS,2S,3S)- Usage And Synthesis |
| Description | Orniplabin, also known as SMTP-7 is a dual inhibitor of thrombolysis and soluble epoxide hydrolase. SMTP-7 promotes thrombolysis and inhibits soluble epoxide hydrolase. | | Uses | Orniplabin (SMTP-7) is a low-molecular-weight compound that enhances plasminogen–fibrin binding, urokinase-catalyzed activation of plasminogen, and urokinase and plasminogen-mediated fibrin degradation. Orniplabin shows potential thrombolytic and anti-inflammatory effects. Orniplabin inhibits ROS[1][2]. | | References | [1] Shibata K, et al. A novel finding of a low-molecular-weight compound, SMTP-7, having thrombolytic and anti-inflammatory effects in cerebral infarction of mice. Naunyn Schmiedebergs Arch Pharmacol. 2010 Sep;382(3):245-53. DOI:10.1007/s00210-010-0542-5
[2] Shibata K, et al. Neuroprotective mechanisms of SMTP-7 in cerebral infarction model in mice. Naunyn Schmiedebergs Arch Pharmacol. 2011 Jul;384(1):103-8. DOI:10.1007/s00210-011-0642-x |
| | Pyrano[2,3-e]isoindole-8(2H)-pentanoic acid, 2-[(3E)-4,8-dimethyl-3,7-nonadien-1-yl]-α-[(2S,3S)-2-[(3E)-4,8-dimethyl-3,7-nonadien-1-yl]-3,4,7,9-tetrahydro-3,5-dihydroxy-2-methyl-7-oxopyrano[2,3-e]isoindol-8(2H)-yl]-3,4,7,9-tetrahydro-3,5-dihydroxy-2-methyl-7-oxo-, (αS,2S,3S)- Preparation Products And Raw materials |
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