1H-Purine-2,6-dione, 1-[11-(dodecylamino)-10-hydroxyundecyl]-3,7-dihydro-3,7-dimethyl- manufacturers
- CT-2584
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- $333.00
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2026-04-20
- CAS:166981-13-1
- Purity: 99.77%
- Supply Ability: 10g
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| | 1H-Purine-2,6-dione, 1-[11-(dodecylamino)-10-hydroxyundecyl]-3,7-dihydro-3,7-dimethyl- Basic information |
| Product Name: | 1H-Purine-2,6-dione, 1-[11-(dodecylamino)-10-hydroxyundecyl]-3,7-dihydro-3,7-dimethyl- | | Synonyms: | 1H-Purine-2,6-dione, 1-[11-(dodecylamino)-10-hydroxyundecyl]-3,7-dihydro-3,7-dimethyl-;1-[11-(Dodecylamino)-10-hydroxyundecyl]-3,7-dihydro-3,7-dimethyl-1H-purine-2,6-dione | | CAS: | 166981-13-1 | | MF: | C30H55N5O3 | | MW: | 533.79 | | EINECS: | | | Product Categories: | | | Mol File: | 166981-13-1.mol | ![1H-Purine-2,6-dione, 1-[11-(dodecylamino)-10-hydroxyundecyl]-3,7-dihydro-3,7-dimethyl- Structure](CAS/20210111/GIF/166981-13-1.gif) |
| | 1H-Purine-2,6-dione, 1-[11-(dodecylamino)-10-hydroxyundecyl]-3,7-dihydro-3,7-dimethyl- Chemical Properties |
| Boiling point | 691.4±53.0 °C(Predicted) | | density | 1.09±0.1 g/cm3(Predicted) | | storage temp. | -20° | | solubility | Soluble in DMSO (up to 25 mg/ml) | | pka | 14.83±0.20(Predicted) | | form | solid | | color | White | | Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months. |
| | 1H-Purine-2,6-dione, 1-[11-(dodecylamino)-10-hydroxyundecyl]-3,7-dihydro-3,7-dimethyl- Usage And Synthesis |
| Description | CT-2584 (166981-13-1; free base) is a cytotoxic agent that alters phospholipid biosynthesis via inhibition of CTP:choline-phosphate cytidylyltransferase causing an increase in phosphatidylinositol with decreasing levels of phosphatidylcholine.1The altered phospholipid metabolism caused by CT-2584 results in a loss of lamellar structure and membrane integrity (especially in mitochondria and endoplasmic reticulum). CT-2584 was active against a wide range of tumor cell lines including multi-drug resistant lines.2 | | Uses | CT-2584 is a chemotherapeutic compound that reduces the expression of NKEF-B in several tumor cell types and kills tumor cells by inducing the production of ROS in mitochondria, commonly used in cancer research[1]. | | References | [1] R E FINNEY. Pharmacological inhibition of phosphatidylcholine biosynthesis is associated with induction of phosphatidylinositol accumulation and cytolysis of neoplastic cell lines.[J]. Cancer research, 2000, 60 18: 5204-5213.
[2] S L CHEESEMAN. Phase I and pharmacologic study of CT-2584 HMS, a modulator of phosphatidic acid, in adult patients with solid tumours[J]. British Journal of Cancer, 2000, 83 12: 1599-1606. DOI:10.1054/bjoc.2000.1503 |
| | 1H-Purine-2,6-dione, 1-[11-(dodecylamino)-10-hydroxyundecyl]-3,7-dihydro-3,7-dimethyl- Preparation Products And Raw materials |
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