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(±)-HIP-A manufacturers
- (±)-HIP-A
-
- $1820.00
-
2026-05-11
- CAS:227619-64-9
- Purity:
- Supply Ability: 10g
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| | (±)-HIP-A Basic information |
| Product Name: | (±)-HIP-A | | Synonyms: | 3-HYDROXY-4,5,6,6A-TETRAHYDRO-3AH-PYRROLO[3,4-D]ISOXAZOLE-4-CARBOXYLIC ACID;HIP-A;2H-Pyrrolo[3,4-d]isoxazole-4-carboxylic acid, hexahydro-3-oxo-, (3aR,4S,6aR)-rel-;(+/-)-HIP-A;(±) HIP A,(±)HIPA;(±)-HIP-A | | CAS: | 227619-64-9 | | MF: | C6H8N2O4 | | MW: | 172.14 | | EINECS: | | | Product Categories: | Glutamate receptor | | Mol File: | 227619-64-9.mol |  |
| | (±)-HIP-A Chemical Properties |
| density | 1.499±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | storage temp. | Store at +4°C | | solubility | Soluble to 10 mM in sterile water | | form | Powder | | pka | 2.320±0.20(predicted) |
| | (±)-HIP-A Usage And Synthesis |
| Uses | (+/-)-HIP-A is anew AMPA-kainate receptor agonist. | | Biological Activity | Potent, non-competitive excitatory amino acid transporter (EAAT) blocker. Preferentially inhibits glutamate-induced [ 3 H]D-aspartate release (IC 50 = 1.6 μ M) rather than [ 3 H]L-glutamate uptake (IC 50 = 18 μ M). Moderately selective; displays no affinity for NMDA and metabotropic glutamate receptors, and low affinity for AMPA and kainate receptors (IC 50 values are 43 and 8 μ M respectively). |
| | (±)-HIP-A Preparation Products And Raw materials |
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