Pyrazolo[1,5-a]pyrido[4,3-d]pyrimidin-9(1H)-one, 7-[2-[4-bromo-5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetyl]-5,6,7,8-tetrahydro-2-phenyl-

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Pyrazolo[1,5-a]pyrido[4,3-d]pyrimidin-9(1H)-one, 7-[2-[4-bromo-5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetyl]-5,6,7,8-tetrahydro-2-phenyl- Suppliers list
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Pyrazolo[1,5-a]pyrido[4,3-d]pyrimidin-9(1H)-one, 7-[2-[4-bromo-5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetyl]-5,6,7,8-tetrahydro-2-phenyl- Basic information
Product Name:Pyrazolo[1,5-a]pyrido[4,3-d]pyrimidin-9(1H)-one, 7-[2-[4-bromo-5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetyl]-5,6,7,8-tetrahydro-2-phenyl-
Synonyms:Pyrazolo[1,5-a]pyrido[4,3-d]pyrimidin-9(1H)-one, 7-[2-[4-bromo-5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetyl]-5,6,7,8-tetrahydro-2-phenyl-
CAS:1775330-54-5
MF:C22H18BrF3N6O2
MW:535.32
EINECS:
Product Categories:
Mol File:1775330-54-5.mol
Pyrazolo[1,5-a]pyrido[4,3-d]pyrimidin-9(1H)-one, 7-[2-[4-bromo-5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetyl]-5,6,7,8-tetrahydro-2-phenyl- Structure
Pyrazolo[1,5-a]pyrido[4,3-d]pyrimidin-9(1H)-one, 7-[2-[4-bromo-5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetyl]-5,6,7,8-tetrahydro-2-phenyl- Chemical Properties
Boiling point 668.5±65.0 °C(Predicted)
density 1.72±0.1 g/cm3(Predicted)
pka8.05±0.20(Predicted)
form Solid
color Off-white to light yellow
Safety Information
MSDS Information
Pyrazolo[1,5-a]pyrido[4,3-d]pyrimidin-9(1H)-one, 7-[2-[4-bromo-5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetyl]-5,6,7,8-tetrahydro-2-phenyl- Usage And Synthesis
UsesPAT1inh-B01 is a selective SLC26A6 inhibitor. PAT1inh-B01 inhibits PAT1 (a Cl-/HCO3- exchanger)-mediated anion exchange (IC50: 350 nM). PAT1inh-B01 blocks fluid absorption in small intestine. PAT1inh-B01 can be used for research of small intestinal hyposecretory disorders[1].
References[1] Cil O, et al. SLC26A6-selective inhibitor identified in a small-molecule screen blocks fluid absorption in small intestine. JCI Insight. 2021 Jun 8;6(11):e147699. DOI:10.1172/jci.insight.147699
Pyrazolo[1,5-a]pyrido[4,3-d]pyrimidin-9(1H)-one, 7-[2-[4-bromo-5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetyl]-5,6,7,8-tetrahydro-2-phenyl- Preparation Products And Raw materials
Tag:Pyrazolo[1,5-a]pyrido[4,3-d]pyrimidin-9(1H)-one, 7-[2-[4-bromo-5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetyl]-5,6,7,8-tetrahydro-2-phenyl-(1775330-54-5) Related Product Information
Pyrazolo[1,5-a]pyrido[4,3-d]pyrimidin-9(1H)-one, 7-[2-[4-bromo-5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetyl]-5,6,7,8-tetrahydro-2-phenyl- 13H-17,20-Methano-8,12-nitrilo-12H-pyrido[3,2-d][1,2,6,13]thiatriazacyclooctadecin-5(6H)-one, 2-[3-(2-dispiro[2.0.2.1]hept-7-ylethoxy)-1H-pyrazol-1-yl]-14,15,16,17,18,19-hexahydro-19,19-dimethyl-, 7,7-dioxide, (17S)- Selamectin Shikonin ARN11391 Ion Channel Compound Library