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- Lavoltidine
-
- $1980.00
-
2026-07-17
- CAS:76956-02-0
- Purity: 98.36%
- Supply Ability: 10g
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| | Lavoltidine Basic information |
| Product Name: | Lavoltidine | | Synonyms: | 1-Methyl-5-[[3-[3-(1-piperidinylmethyl)phenoxy]propyl]amino]-1H-1,2,4-triazole-3-methanol;1H-1,2,4-Triazole-3-methanol, 1-methyl-5-((3-(3-(1-piperidinylmethyl)phenoxy)propyl)amino)-;Lavoltidina;Lavoltidina [inn-spanish];Lavoltidine [inn:ban];Lavoltidinum;Lavoltidinum [inn-latin];Loxtidina | | CAS: | 76956-02-0 | | MF: | C19H29N5O2 | | MW: | 359.471 | | EINECS: | | | Product Categories: | | | Mol File: | 76956-02-0.mol |  |
| | Lavoltidine Chemical Properties |
| | Lavoltidine Usage And Synthesis |
| Uses | Anti-ulcerative (histamine H2-receptor block er). | | Definition | ChEBI: Loxtidine is a triazole that consists of 1,2,4-triazole bearing a methyl substituent at position 1, a hydroxymethyl substituent at position 3 and a {3-[3-(piperidin-1-ylmethyl)phenoxy]propyl}amino group at position 5. A highly potent and selective H2-receptor antagonist. It has a role as a H2-receptor antagonist. It is a member of triazoles, a member of piperidines, an aromatic ether and a primary alcohol. | | in vivo | Lavoltidine (Loxtidine; 0.5 g/L; orally (drinking water); changed weekly; for 3 months) shows partial suppression of both gastric acid secretion and progression to neoplasia. Lavoltidine inhibits gastric atrophy, hyperplasia, and dysplasia in H felis-infected INS-GAS mice[1].
Lavoltidine treatment for 6 months inhibits gastric tumors in H felis-infected INS-GAS mice[1].
| Animal Model: | Male hypergastrinemic mice (INS-GAS mice) infected with Helicobacter felis[1] | | Dosage: | 0.5 g/L | | Administration: | Orally (drinking water); changed weekly; for 3 months | | Result: | Showed partial suppression of both gastric acid secretion and progression to neoplasia.
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| | IC 50 | H2 Receptor |
| | Lavoltidine Preparation Products And Raw materials |
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