- Nemadectin
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2025-04-04
- CAS:102130-84-7
- Min. Order: 25KG
- Purity: 97%
- Supply Ability: 1tone
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| | Nemadectin Basic information |
| Product Name: | Nemadectin | | Synonyms: | Nemadectin;(6R,23S,25S)-5-O-Demethyl-28-deoxy-25-[(E)-1,3-dimethyl-1-butenyl]-6,28-epoxy-23-hydroxymilbemycin B;AC-088;LL-F-28249α;S541A, LL-F28249 alpha;LL-F28249 alpha;Milbemycin B,5-O-demethyl-28-deoxy-25-[(1E)-1,3-dimethyl-1-buten-1-yl]-6,28-epoxy-23-hydroxy-,(6R,23S)-;(2R,2a'E,2a1'S,4S,4'E,5S,6S,6'R,8'E,11'R,15'S,17a'R,20'R,20a'R)-2a1',4,20'-Trihydroxy-5,6',8',19'-tetramethyl-6-((E)-4-methylpent-2-en-2-yl)-2a1',3,4,5,6,6',7',10',11',14',15',17a',20',20a'-tetradecahydro-2'H,17'H-spiro[pyran-2,13'-[11,15]methano[1,5]dioxacyclooctadecino[9,8,7-cd]benzofuran]-17'-one | | CAS: | 102130-84-7 | | MF: | C36H52O8 | | MW: | 612.79 | | EINECS: | | | Product Categories: | | | Mol File: | 102130-84-7.mol |  |
| | Nemadectin Chemical Properties |
| alpha | D26 +133° (c = 0.3 in acetone) | | Boiling point | 789.4±60.0 °C(Predicted) | | density | 1.20±0.1 g/cm3(Predicted) | | pka | 12.46±0.70(Predicted) | | form | Solid | | color | White to off-white | | InChIKey | YNFMRVVYUVPIAN-JUOPSJISNA-N |
| RIDADR | 2588 | | HazardClass | 6.1(b) | | PackingGroup | III |
| | Nemadectin Usage And Synthesis |
| Description | The nemadectins are fermentation products of Streptomyces
cyaneogriseus noncyanogenus. Structurally, the
nemadectins lack a disaccharide group at C-13 but differ
from the milbemycins proper because they contain a
trisubstituted double bond at C-26 in their side chains. | | Uses | Nemadectin is a potent antiparasitic macrolide lactone. | | Uses | Nemadectin is the dominant member of a class of milbemycins bearing unsaturated longer chain groups at the 25-position. Nemadectin shows pronounced nematocidal and insecticidal activity. Nemadectin is the starting material for moxidectin, a commercial anthelmintic. | | in vivo | Nemadectin is highly effective at 0.6 mg/kg BW against natural infections of all major species of canine intestinal helminths, when administered as a single oral dose, either as a liquid or a tablet[1]. | | IC 50 | Mite |
| | Nemadectin Preparation Products And Raw materials |
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