lupanine manufacturers
- Lupanine
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2026-09-10
- CAS:550-90-3
- Purity:
- Supply Ability: 10g
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| | lupanine Basic information |
| Product Name: | lupanine | | Synonyms: | (7aβ,14aα)-Dodecahydro-7α,14α-methano-4H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-4-one;2-Oxosparteine;d-Lupanine;LUPANINE(SH);lupanine;7,14-Methano-2H,11H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-11-one,dodecahydro-, (7S,7aR,14S,14aS)-;Lupanin | | CAS: | 550-90-3 | | MF: | C15H24N2O | | MW: | 248.36 | | EINECS: | | | Product Categories: | | | Mol File: | 550-90-3.mol |  |
| | lupanine Chemical Properties |
| Melting point | 40-44° | | alpha | D25 +84° (c = 4.8 in alc) | | Boiling point | bp3 190-193° | | density | 0.9789 (rough estimate) | | refractive index | nD24 1.5444 | | form | Liquid | | pka | 9.47±0.20(Predicted) | | color | Colorless to light yellow |
| | lupanine Usage And Synthesis |
| Uses | (+)-Lupanine is used in biological studies with quinolizidine alkaloids in seeds of lupin genotypes of different origins. | | Definition | ChEBI: The delta-lactam obtained by formal oxidation at the 2-position of sparteine. The major alkaloid from the seeds of Lupinus exaltatus, L. mexicanus and L. rotundiflorus, it is among the most important of the tetracyc
ic quinolizidine alkaloids. | | in vivo | Lupanine (100-300 mg/kg for i.p.; 175-700 mg/kg for p.o.) is much less toxic in one single injection in EOPS male Swiss mice (20-22 g) and Hartley guinea-pigs (400-500 g)[1].
Lupanine (1-7.5 mg/kg; i.v.) is more efficient than Sparteine for antagonizing secondary reflex hypertension in carotid occlusion and hypotension resulting from the stimulation of the pneumogastric nerve in both the cat and the dog[1].
Lupanine has an inhibitory action on nicotinic type hypertension produced by injection of Acetylcholine (500 p.g/kg i.v.) in the Atropine-treated dog[1].
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| | lupanine Preparation Products And Raw materials |
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