7-BROMO-1H-QUINAZOLIN-4-ONE

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7-BROMO-1H-QUINAZOLIN-4-ONE Suppliers list
Company Name: Capot Chemical Co.,Ltd.
Tel: +8613336195806
Email: sales@capot.com
Products Intro: Product Name:7-Bromoquinazolin-4(3H)-one
CAS:194851-16-6
Purity:98% (Min,GC) Package:100g;1kg;5kg,10kg,25kg,50kg
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
Products Intro: Product Name:7-BROMO-1H-QUINAZOLIN-4-ONE
CAS:194851-16-6
Purity:98% HPLC Package:5G;10G;25G;50G;100G;250G;1KG
Company Name: Alchem Pharmtech,Inc.
Tel: 8485655694
Email: sales@alchempharmtech.com
Products Intro: Product Name:7-Bromoquinazolin-4(3H)-one
CAS:194851-16-6
Purity:97+% Package:1g;10g;100g;;1kg Remarks:Z-01551
Company Name: career henan chemical co
Tel: +86-0371-86658258 +8613203830695
Email: factory@coreychem.com
Products Intro: Product Name:7-BROMO-1H-QUINAZOLIN-4-ONE
CAS:194851-16-6
Purity:99% Package:1g;1USD
Company Name: Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
Tel: +8613580539051
Email: joe@yuhengpharm.com
Products Intro: Product Name:7-bromo-3,4-dihydroquinazolin-4-one
CAS:194851-16-6
Purity:0.97 Package:1KG;25KG

7-BROMO-1H-QUINAZOLIN-4-ONE manufacturers
7-BROMO-1H-QUINAZOLIN-4-ONE Basic information
Application
Product Name:7-BROMO-1H-QUINAZOLIN-4-ONE
Synonyms:7-BroMoquinazolin-4-one;7-BroMo-3,4-dihydroquinaz...;7-Bromo-4-quinazolone;7-BroMoquinazolin-4(1H)-one;7-bromoquinazoL;7-Bromo-3H-quizolin-4-one;7-BroMo-3,4-dihydroquinazolin-4-one, 95+%;7-Bromo-3H-quinazolin-4-one
CAS:194851-16-6
MF:C8H5BrN2O
MW:225.04
EINECS:
Product Categories:Halides;CHIRAL CHEMICALS;Fused Ring Systems
Mol File:194851-16-6.mol
7-BROMO-1H-QUINAZOLIN-4-ONE Structure
7-BROMO-1H-QUINAZOLIN-4-ONE Chemical Properties
Boiling point 350.1±44.0 °C(Predicted)
density 1.82±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka0.36±0.20(Predicted)
AppearanceWhite to off-white Solid
Safety Information
Risk Statements 36
Safety Statements 26
HS Code 2914390090
MSDS Information
7-BROMO-1H-QUINAZOLIN-4-ONE Usage And Synthesis
Application7-Bromo-3,4-dihydroquinazolin-4-one is a quinazolone compound. Quinazolones are a class of nitrogen-containing heterocyclic compounds with good biomedical activity, due to their broad range of biological and pharmaceutical activities.
Synthesis
2-Amino-4-bromobenzoic acid

20776-50-5

formamide

77287-34-4

7-BROMO-1H-QUINAZOLIN-4-ONE

194851-16-6

General procedure for the synthesis of 7-bromo-3,4-dihydroquinazolin-4-one from 2-amino-4-bromobenzoic acid and compound (CAS: 77287-34-4): 0.0 g (1.56 mol) of 2-amino-4-bromobenzoic acid was suspended in 970 mL of formamide, followed by stirring of the reaction for 12 hours at 170°C. Upon completion of the reaction, a conventional post-processing was carried out to give 326.0 g of 7-bromo-3H-quinazolin-4-one; which was analyzed by HPLC/MS as a solid product with (M + H)+ = 226.

References[1] Patent: US2013/12489, 2013, A1. Location in patent: Paragraph 0182
[2] Patent: WO2010/146173, 2010, A1. Location in patent: Page/Page column 16
[3] Patent: CN105503744, 2016, A. Location in patent: Paragraph 0033; 0036; 0037
[4] Journal of Organic Chemistry, 1952, vol. 17, p. 149,153
[5] Patent: US2016/31860, 2016, A1. Location in patent: Paragraph 0110; 0111
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