7-Bromo-1H-quinazolin-4-one

7-Bromo-1H-quinazolin-4-one Suppliers list

Company Name:	Yantai Sheng Kai Lun Biological Products Co. , Ltd. Gold
Tel:	13356901049
Email:	mark@sklnchem.cn

Company Name:	Beijing Ouhe Technology Co., Ltd
Tel:	13552068683 13522913783
Email:	2355560935@qq.com

7-Bromo-1H-quinazolin-4-one manufacturers

7-Bromo-1H-quinazolin-4-one Basic information

Product Name:	7-Bromo-1H-quinazolin-4-one
Synonyms:	7-BroMoquinazolin-4-one;7-BroMo-3,4-dihydroquinaz...;7-Bromo-4-quinazolone;7-BroMoquinazolin-4(1H)-one;7-bromoquinazoL;7-Bromo-3H-quizolin-4-one;7-BroMo-3,4-dihydroquinazolin-4-one, 95+%;7-Bromo-3H-quinazolin-4-one
CAS:	194851-16-6
MF:	C8H5BrN2O
MW:	225.04
EINECS:
Product Categories:	Halides;CHIRAL CHEMICALS;Fused Ring Systems
Mol File:	194851-16-6.mol

7-Bromo-1H-quinazolin-4-one Chemical Properties

Boiling point	350.1±44.0 °C(Predicted)
density	1.82±0.1 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
pka	0.36±0.20(Predicted)
Appearance	White to off-white Solid

Safety Information

MSDS Information

7-Bromo-1H-quinazolin-4-one Usage And Synthesis

Application	7-Bromo-3,4-dihydroquinazolin-4-one is a quinazolone compound. Quinazolones are a class of nitrogen-containing heterocyclic compounds with good biomedical activity, due to their broad range of biological and pharmaceutical activities.
Synthesis	20776-50-5 77287-34-4 194851-16-6 General procedure for the synthesis of 7-bromo-3,4-dihydroquinazolin-4-one from 2-amino-4-bromobenzoic acid and compound (CAS: 77287-34-4): 0.0 g (1.56 mol) of 2-amino-4-bromobenzoic acid was suspended in 970 mL of formamide, followed by stirring of the reaction for 12 hours at 170°C. Upon completion of the reaction, a conventional post-processing was carried out to give 326.0 g of 7-bromo-3H-quinazolin-4-one; which was analyzed by HPLC/MS as a solid product with (M + H)+ = 226.
References	[1] Patent: US2013/12489, 2013, A1. Location in patent: Paragraph 0182 [2] Patent: WO2010/146173, 2010, A1. Location in patent: Page/Page column 16 [3] Patent: CN105503744, 2016, A. Location in patent: Paragraph 0033; 0036; 0037 [4] Journal of Organic Chemistry, 1952, vol. 17, p. 149,153 [5] Patent: US2016/31860, 2016, A1. Location in patent: Paragraph 0110; 0111

7-Bromo-1H-quinazolin-4-one Preparation Products And Raw materials

Raw materials

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