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| | 7-BROMO-2-METHYL-2H-INDAZOLE Basic information |
| | 7-BROMO-2-METHYL-2H-INDAZOLE Chemical Properties |
| storage temp. | Sealed in dry,Room Temperature | | form | solid | | Appearance | yellow solid | | InChI | 1S/C8H7BrN2/c1-11-5-6-3-2-4-7(9)8(6)10-11/h2-5H,1H3 | | InChIKey | KPAYIFGPJOYWMM-UHFFFAOYSA-N | | SMILES | Cn1cc2cccc(Br)c2n1 |
| Hazard Codes | Xn | | Risk Statements | 22 | | WGK Germany | 3 | | HS Code | 2933998090 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Acute Tox. 4 Oral |
| | 7-BROMO-2-METHYL-2H-INDAZOLE Usage And Synthesis |
| Synthesis | Example 3: Synthesis of 7-(2,4-dichlorophenyl)-2,3-dimethyl-2H-indazole hydrochloride
Step 1: To 30 mL of toluene, 7-bromo-1H-indazole (3; 1.71 g, 8.67 mmol) and dimethyl sulfate (0.90 mL, 9.5 mmol) were added. The reaction mixture was stirred at 110 °C for 4 h and subsequently cooled to room temperature. Upon completion of the reaction, the mixture was carefully washed with 30 mL of saturated aqueous NaHCO3 to neutralize the unreacted dimethyl sulfate. The organic layer was dried over anhydrous MgSO4, filtered (the filter cake was washed with ether) and concentrated under reduced pressure to give an orange colored oil. Purification by column chromatography (eluent: 0-50% EtOAc/hexane) afforded 7-bromo-2-methyl-2H-indazole (6: R = Me; 1.33 g, 73%) as a light tan solid. | | References | [1] Patent: WO2005/16892, 2005, A1. Location in patent: Page/Page column 70-71 |
| | 7-BROMO-2-METHYL-2H-INDAZOLE Preparation Products And Raw materials |
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