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| | 8-(2-[7-Nitro-4-benzofurazanyl]aminoethylthio]guanosine-3',5'-cyclic monophosphate sodium salt Basic information |
| Product Name: | 8-(2-[7-Nitro-4-benzofurazanyl]aminoethylthio]guanosine-3',5'-cyclic monophosphate sodium salt | | Synonyms: | 8-[[2-[(7-nitro-4-benzofurazanyl)amino]ethyl]thio]guanosine-3’,5’-cyclicmonophosphate(8-nbd-cgmp;8-NBD-CGMP, NA;8-NBD-CGMP SODIUM SALT;GUANOSINE-3',5'-CYCLIC MONOPHOSPHATE, 8-[[2-[(7-NITRO-4-BENZOFURANZANYL)AMINO]ETHYL]THIO]-, SODIUM SALT;8-{{2-[(7-Nitro-4-benzofurazanyl)-amino]-ethyl}-thio}-guanosine-3'',5''-cycli;Guanosine, 8-[[2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]ethyl]thio]-, cyclic 3',5'-(hydrogen phosphate) (9CI);8-NBD-cGMP;8-(2-[7-Nitro-4-benzofurazanyl]aminoethylthio]guanosine-3',5'-cyclic monophosphate sodium salt | | CAS: | 115993-88-9 | | MF: | C18H18N9O10PS | | MW: | 583.43 | | EINECS: | | | Product Categories: | | | Mol File: | 115993-88-9.mol | ![8-(2-[7-Nitro-4-benzofurazanyl]aminoethylthio]guanosine-3',5'-cyclic monophosphate sodium salt Structure](CAS/GIF/115993-88-9.gif) |
| | 8-(2-[7-Nitro-4-benzofurazanyl]aminoethylthio]guanosine-3',5'-cyclic monophosphate sodium salt Chemical Properties |
| | 8-(2-[7-Nitro-4-benzofurazanyl]aminoethylthio]guanosine-3',5'-cyclic monophosphate sodium salt Usage And Synthesis |
| Uses | 8-NBD-cGMP is a fluorescent analog of cyclic guanosine monophosphate and a potent, membrane-permeable, fluorescent activator of cGMP-dependent protein kinase isozymes I α and I β. 8-NBD-cGMP is barely fluorescent in aqueous solution but fluoresces strongly in hydrophobic environments such as hydrophobic protein binding sites[1] | | References | [1] Schmidpeter, et al. Ligand binding and activation properties of the purified bacterial cyclic nucleotide–gated channel SthK. Journal of General Physiology 150.6 (2018): 821-834. DOI:10.1085/jgp.201812023 |
| | 8-(2-[7-Nitro-4-benzofurazanyl]aminoethylthio]guanosine-3',5'-cyclic monophosphate sodium salt Preparation Products And Raw materials |
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