8-(2-[7-Nitro-4-benzofurazanyl]aminoethylthio]guanosine-3',5'-cyclic monophosphate sodium salt

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8-(2-[7-Nitro-4-benzofurazanyl]aminoethylthio]guanosine-3',5'-cyclic monophosphate sodium salt Basic information
Product Name:8-(2-[7-Nitro-4-benzofurazanyl]aminoethylthio]guanosine-3',5'-cyclic monophosphate sodium salt
Synonyms:8-[[2-[(7-nitro-4-benzofurazanyl)amino]ethyl]thio]guanosine-3’,5’-cyclicmonophosphate(8-nbd-cgmp;8-NBD-CGMP, NA;8-NBD-CGMP SODIUM SALT;GUANOSINE-3',5'-CYCLIC MONOPHOSPHATE, 8-[[2-[(7-NITRO-4-BENZOFURANZANYL)AMINO]ETHYL]THIO]-, SODIUM SALT;8-{{2-[(7-Nitro-4-benzofurazanyl)-amino]-ethyl}-thio}-guanosine-3'',5''-cycli;Guanosine, 8-[[2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]ethyl]thio]-, cyclic 3',5'-(hydrogen phosphate) (9CI);8-NBD-cGMP;8-(2-[7-Nitro-4-benzofurazanyl]aminoethylthio]guanosine-3',5'-cyclic monophosphate sodium salt
CAS:115993-88-9
MF:C18H18N9O10PS
MW:583.43
EINECS:
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Mol File:115993-88-9.mol
8-(2-[7-Nitro-4-benzofurazanyl]aminoethylthio]guanosine-3',5'-cyclic monophosphate sodium salt Structure
8-(2-[7-Nitro-4-benzofurazanyl]aminoethylthio]guanosine-3',5'-cyclic monophosphate sodium salt Chemical Properties
Safety Information
MSDS Information
8-(2-[7-Nitro-4-benzofurazanyl]aminoethylthio]guanosine-3',5'-cyclic monophosphate sodium salt Usage And Synthesis
Uses8-NBD-cGMP is a fluorescent analog of cyclic guanosine monophosphate and a potent, membrane-permeable, fluorescent activator of cGMP-dependent protein kinase isozymes I α and I β. 8-NBD-cGMP is barely fluorescent in aqueous solution but fluoresces strongly in hydrophobic environments such as hydrophobic protein binding sites[1]
References[1] Schmidpeter, et al. Ligand binding and activation properties of the purified bacterial cyclic nucleotide–gated channel SthK. Journal of General Physiology 150.6 (2018): 821-834. DOI:10.1085/jgp.201812023
8-(2-[7-Nitro-4-benzofurazanyl]aminoethylthio]guanosine-3',5'-cyclic monophosphate sodium salt Preparation Products And Raw materials
Tag:8-(2-[7-Nitro-4-benzofurazanyl]aminoethylthio]guanosine-3',5'-cyclic monophosphate sodium salt(115993-88-9) Related Product Information
8-(2-[7-Nitro-4-benzofurazanyl]aminoethylthio]guanosine-3',5'-cyclic monophosphate sodium salt 5-Amino-1-methyl-2-(methylthio)-1H-imidazole-4-carboxamide 8-(2-Aminoethylthio) guanosine-3',5'-cyclic monophosphate sodium salt 5-Amino-2-mercapto-1-methyl-1H-imidazole-4-carboxamide 8-MERCAPTOGUANOSINE GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SODIUM SALT 2'-DCGMP SODIUM SALT