Piperidine, 3-methyl-1-[[3-methyl-4-(1-methylethyl)-5-oxo-2(5H)-isoxazolyl]carbonyl]-, (3S)- (9CI)

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Piperidine, 3-methyl-1-[[3-methyl-4-(1-methylethyl)-5-oxo-2(5H)-isoxazolyl]carbonyl]-, (3S)- (9CI) Suppliers list
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Piperidine, 3-methyl-1-[[3-methyl-4-(1-methylethyl)-5-oxo-2(5H)-isoxazolyl]carbonyl]-, (3S)- (9CI) manufacturers

  • BAY 59-9435
  • BAY 59-9435 pictures
  • $2500.00
  • 2026-05-11
  • CAS:654059-21-9
  • Purity:
  • Supply Ability: 10g
  • BAY 59-9435
  • BAY 59-9435 pictures
  • $2500.00
  • 2025-07-20
  • CAS:654059-21-9
  • Purity:
  • Supply Ability: 10g
Piperidine, 3-methyl-1-[[3-methyl-4-(1-methylethyl)-5-oxo-2(5H)-isoxazolyl]carbonyl]-, (3S)- (9CI) Basic information
Product Name:Piperidine, 3-methyl-1-[[3-methyl-4-(1-methylethyl)-5-oxo-2(5H)-isoxazolyl]carbonyl]-, (3S)- (9CI)
Synonyms:Piperidine, 3-methyl-1-[[3-methyl-4-(1-methylethyl)-5-oxo-2(5H)-isoxazolyl]carbonyl]-, (3S)- (9CI);(S)-4-Isopropyl-3-methyl-2-(3-methylpiperidine-1-carbonyl)isoxazol-5(2H)-one;HSL inhibitor 2;5(2H)-Isoxazolone, 3-methyl-4-(1-methylethyl)-2-[[(3S)-3-methyl-1-piperidinyl]carbonyl]-;BAY 59-9435;BAY 59 9435,BAY 599435
CAS:654059-21-9
MF:C14H22N2O3
MW:266.34
EINECS:
Product Categories:
Mol File:654059-21-9.mol
Piperidine, 3-methyl-1-[[3-methyl-4-(1-methylethyl)-5-oxo-2(5H)-isoxazolyl]carbonyl]-, (3S)- (9CI) Structure
Piperidine, 3-methyl-1-[[3-methyl-4-(1-methylethyl)-5-oxo-2(5H)-isoxazolyl]carbonyl]-, (3S)- (9CI) Chemical Properties
Boiling point 345.8±25.0 °C(Predicted)
density 1.140±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO: 250 mg/mL (938.65 mM)
form Solid
pka-1.21±0.40(Predicted)
color White to off-white
Safety Information
MSDS Information
Piperidine, 3-methyl-1-[[3-methyl-4-(1-methylethyl)-5-oxo-2(5H)-isoxazolyl]carbonyl]-, (3S)- (9CI) Usage And Synthesis
UsesBAY 59-9435 is a potent and selective inhibitor of Hormone Sensitive Lipase (HSL), with an IC50 of 0.023 μM.
References[1] Ebdrup S, et al. Synthesis and structure-activity relationship for a novel class of potent and selective carbamoyl-triazole based inhibitors of hormone sensitive lipase. J Med Chem. 2004 Jan 15;47(2):400-10. DOI:10.1021/jm031004s
[2] Elizabeth A Rondini, et al. Novel Pharmacological Probes Reveal ABHD5 as a Locus of Lipolysis Control in White and Brown AdipocytesJ Pharmacol Exp Ther. 2017 Dec;363(3):367-376. DOI:10.1124/jpet.117.243253
[3] Wenliang Zhang, et al. Adipocyte lipolysis-stimulated interleukin-6 production requires sphingosine kinase 1 activity. J Biol Chem. 2014 Nov 14;289(46):32178-85. DOI:10.1074/jbc.M114.601096
Piperidine, 3-methyl-1-[[3-methyl-4-(1-methylethyl)-5-oxo-2(5H)-isoxazolyl]carbonyl]-, (3S)- (9CI) Preparation Products And Raw materials
Tag:Piperidine, 3-methyl-1-[[3-methyl-4-(1-methylethyl)-5-oxo-2(5H)-isoxazolyl]carbonyl]-, (3S)- (9CI)(654059-21-9) Related Product Information
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