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| | n-Dodecyl-beta-D-maltoside Basic information |
| Product Name: | n-Dodecyl-beta-D-maltoside | | Synonyms: | N-Dodecyl-b-maltoside;Detergent Screening Solution 26/Fluka kit no 66317;Dodecyl β-D-maltoside solution;Dodecyl-4-O-alpha-d-glucopyranosyl-betaDglucopyranoside;N-Dodecyl-Beta-D-Maltoaside;2XYT MEDIUM BROTH E;(2R,3R,4S,5S,6R)-2-(((2R,3S,4R,5R,6R)-6-(Dodecyloxy)-4,5-dihydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol;n-Dodecyl-β-D-maltopyranoside 〔n-Dodecyl-β-D-maltoside〕 | | CAS: | 69227-93-6 | | MF: | C24H46O11 | | MW: | 510.62 | | EINECS: | 614-943-6 | | Product Categories: | detergent;Glycon Biochem | | Mol File: | 69227-93-6.mol |  |
| | n-Dodecyl-beta-D-maltoside Chemical Properties |
| Melting point | 224-226 °C(lit.) | | alpha | 47.5 º (c=1, water) | | Boiling point | 703.5±60.0 °C(Predicted) | | density | 1.28±0.1 g/cm3(Predicted) | | storage temp. | Inert atmosphere,Store in freezer, under -20°C | | solubility | DMF: 20 mg/ml
DMSO: 10 mg/ml
Ethanol: 10 mg/mlPBS (pH 7.2): 2 mg/ml | | pka | 12.82±0.70(Predicted) | | form | Powder | | color | White to off-white | | Water Solubility | soluble | | BRN | 55318 | | Stability: | Stable, but store cool. Incompatible with strong oxidizing agents. | | Major Application | (solubilizing, purifying, and stabilizing membrane proteins) | | InChIKey | NLEBIOOXCVAHBD-KJPZNAOGNA-N | | SMILES | O([C@]1([H])[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@H]1[C@@H]([C@@H](O)[C@H](OCCCCCCCCCCCC)O[C@@H]1CO)O |&1:1,3,4,6,8,13,14,15,17,32,r| |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 24/25-36/37/39 | | WGK Germany | 3 | | F | 3-10 | | HS Code | 29400090 | | Storage Class | 11 - Combustible Solids |
| | n-Dodecyl-beta-D-maltoside Usage And Synthesis |
| Chemical Properties | white powder | | Uses | N-dodecyl-β-D-maltoside is used as a non-ionic detergent for stabilization and activation of enzymes and for membrane research. It has also been used for the isolation of the mitochondrial cytochrome c oxidize. | | Definition | ChEBI: A glycoside resulting from attachment of a dodecyl group to the reducing-end anomeric centre of a beta-maltose molecule. | | General Description | Absorbance (10%, H2O, 260 nm): <1.0. | | References | [1] PHILIPP ELLINGER. Detergent screening and purification of the human liver ABC transporters BSEP (ABCB11) and MDR3 (ABCB4) expressed in the yeast Pichia pastoris.[J]. PLoS ONE, 2013: e60620. DOI: 10.1371/journal.pone.0060620
[2] SARAH L ROUSE. Dodecyl maltoside protects membrane proteins in vacuo.[J]. Biophysical journal, 2013, 105 3: 648-656. DOI: 10.1016/j.bpj.2013.06.025
[3] KOCH K W. Purification and identification of photoreceptor guanylate cyclase.[J]. The Journal of Biological Chemistry, 1991, 1 1: 8634-8637. DOI: 10.1016/s0021-9258(18)93021-8
[4] BÉATRICE DE FORESTA Philippe C Fernando HENAO. Cancellation of the cooperativity of Ca2+ binding to sarcoplasmic reticulum Ca2+-ATPase by the non-ionic detergent dodecylmaltoside[J]. The FEBS journal, 1994, 223 2: 359-369. DOI: 10.1111/j.1432-1033.1994.tb19002.x
[5] G. ZARDENETA P M H. Micelle-assisted protein folding. Denatured rhodanese binding to cardiolipin-containing lauryl maltoside micelles results in slower refolding kinetics but greater enzyme reactivation.[J]. The Journal of Biological Chemistry, 1992, 28 1: 5811-5816. DOI: 10.1016/s0021-9258(18)42625-7
[6] ANNE WALTER. The vesicle-to-micelle transition of phosphatidylcholine vesicles induced by nonionic detergents: effects of sodium chloride, sucrose and urea[J]. Biochimica et biophysica acta. Biomembranes, 2000, 1508 1: Pages 20-33. DOI: 10.1016/s0304-4157(00)00005-8 |
| | n-Dodecyl-beta-D-maltoside Preparation Products And Raw materials |
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