D-Myo-inositol 1-monophosphate cyclohexylammonium salt

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D-Myo-inositol 1-monophosphate cyclohexylammonium salt Basic information
Product Name:D-Myo-inositol 1-monophosphate cyclohexylammonium salt
Synonyms:D-myo-inositol 1-monophosphate;D-myo-inositol 1-monophosphate bis(cyclo -hexylamine) salt S;D-MYO-INOSITOL 1-MONOPHOSPHATE*CYCLOHEXY LAMMONIUM;D-MYO-INOSITOL 1-MONOPHOSPHATE BIS(CYCL&;D-myo-inositol 1-monophosphate bis(cyclohexylamine) salt;D-myo-Inositol 1-monophosphate bis(cyclohexylammonium) salt;D-myo-Inositol-1-phosphate cyclohexylammonium salt;D-myo-Inositol, 1-(dihydrogen phosphate), compd. with cyclohexanamine
CAS:106032-59-1
MF:C6H13N.C6H13O9P
MW:359.31
EINECS:
Product Categories:Carbohydrates;Carbohydrates A to;Carbohydrates H-LBiochemicals and Reagents;Monosaccharide
Mol File:106032-59-1.mol
D-Myo-inositol 1-monophosphate cyclohexylammonium salt Structure
D-Myo-inositol 1-monophosphate cyclohexylammonium salt Chemical Properties
Fp 14 °C
storage temp. −20°C
solubility Water: > 1mg/ml
form lyophilized powder
color White to off-white
Water Solubility Soluble in water
Safety Information
Hazard Codes F,Xi
Risk Statements 11-36/37/38
Safety Statements 26-36
RIDADR UN 1993 3/PG 2
WGK Germany 3
F 3-10
MSDS Information
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SigmaAldrich English
D-Myo-inositol 1-monophosphate cyclohexylammonium salt Usage And Synthesis
DescriptionD-myo-Inositol-1-phosphate (Ins(1)P1) is a member of the inositol phosphate molecular family of second messengers that play critical roles in intracellular signaling.1,2 Ins(1)P1 can be formed by PLC hydrolysis of phosphatidylinositol or by dephosphorylation of polyphosphate inositols such as Ins(1,3)P2 by inositol polyphosphate 3-phosphatase.1 Changes in myo-inositol-1-phosphate synthase activity and inositol levels are induced by lithium and valproate and are associated with bipolar disorder.3,4 Also, cross-regulation occurs between the SUMO and inositol pathways.5WARNING This product is not for human or veterinary use.
References[1] MAJERUS P W. Inositol phosphate biochemistry.[J]. Annual review of biochemistry, 1992, 61: 225-250. DOI: 10.1146/annurev.bi.61.070192.001301
[2] BERRIDGE M J. Inositol trisphosphate and calcium signalling[J]. Nature, 1993, 361 6410: 315-325. DOI: 10.1038/361315a0
[3] ALON SHAMIR. Human MIP synthase splice variants in bipolar disorder[J]. Bipolar Disorders, 2007, 9 7: 766-771. DOI: 10.1111/j.1399-5618.2007.00440.x
[4] LORETTA M. HALLCHERS W S. The effects of lithium ion and other agents on the activity of myo-inositol-1-phosphatase from bovine brain.[J]. The Journal of Biological Chemistry, 1980, 28 1: 10896-10901. DOI: 10.1016/s0021-9258(19)70391-3
[5] RACHAEL FELBERBAUM. Desumoylation of the endoplasmic reticulum membrane VAP family protein Scs2 by Ulp1 and SUMO regulation of the inositol synthesis pathway.[J]. Molecular and Cellular Biology, 2012, 32 1: 64-75. DOI: 10.1128/mcb.05878-11
D-Myo-inositol 1-monophosphate cyclohexylammonium salt Preparation Products And Raw materials
Tag:D-Myo-inositol 1-monophosphate cyclohexylammonium salt(106032-59-1) Related Product Information
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