| Company Name: |
Alfa Aesar |
| Tel: |
400-6106006 |
| Email: |
saleschina@alfa-asia.com |
PROTOPORPHYRINATO ZINC manufacturers
- PROTOPORPHYRINATO ZINC
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- $1.10
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2026-08-20
- CAS:15442-64-5
- Min. Order: 1g
- Purity: 99.00%
- Supply Ability: 100 Tons Min
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| | PROTOPORPHYRINATO ZINC Basic information |
| Product Name: | PROTOPORPHYRINATO ZINC | | Synonyms: | PROTOPORPHYRINATO ZINC;dihydrogen [3,8,13,17-tetramethyl-7,12-divinyl-21H,23H-porphine-2,18-dipropionato(4-)-N21,N22,N23,N24]zincate(4-);Zinc protoporphyrin trihydrate;Zinc protoporphyrin trihydrate, 95+%;Zinc (II) Protoporphyrin IX - CAS 15442-64-5 - Calbiochem;PROTOPORPHYRINATO ZINC ISO 9001：2015 REACH;Zinc Protoporphyrin IX
DISCONTINUED, offer Z439970;Zinc(II) 3,3'-(3,8,13,17-tetramethyl-7,12-divinylporphyrin-2,18-diyl)dipropionate | | CAS: | 15442-64-5 | | MF: | C34H31N4O4Zn- | | MW: | 625.03 | | EINECS: | 239-455-7 | | Product Categories: | Natural Porphyrins and Derivitives;Porphyrins;metal porphine (porphyrin) complex;1 | | Mol File: | 15442-64-5.mol |  |
| | PROTOPORPHYRINATO ZINC Chemical Properties |
| RTECS | ZG9210300 | | storage temp. | Inert atmosphere,2-8°C | | solubility | DMSO : 50 mg/mL (79.87 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble) | | form | Crystalline | | color | Dark red to purple | | Water Solubility | Insoluble in water. Soluble in ethanol, and DMSO, pyridine, or dimethyl formamide. | | λmax | 426 nm | | ε(extinction coefficient) | ≥10000 at 585-591nm in pyridine
≥12000 at 548-554nm in pyridine
≥135000 at 423-429nm in pyridine | | Stability: | Hygroscopic | | InChIKey | FUTVBRXUIKZACV-RGGAHWMASA-K | | SMILES | C(C1C(=C2C=C3C(C=C)=C(C)C4C=C5C(C=C)=C(C)C6=CC7C(C)=C(CCC(=O)[O-])C8N=7[Zn+2]([N-]56)(N3=4)[N-]2C=1C=8)C)CC(=O)[O-].[H+] | | EPA Substance Registry System | Zincate(2-), [7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-.kappa.N21,.kappa.N22,.kappa.N23,.kappa.N24]-, dihydrogen, (SP-4-2)- (15442-64-5) |
| WGK Germany | 3 | | TSCA | TSCA listed | | Storage Class | 11 - Combustible Solids |
| | PROTOPORPHYRINATO ZINC Usage And Synthesis |
| Uses | Zinc Protoporphyrin is a metabolite formed during biosynthesis and is used to evaluate iron nutrition and metabolism. | | General Description | A potent and selective inhibitor of heme oxygenase, the enzyme which generates carbon monoxide (CO) and biliverdin. Inhibits soluble guanylyl cyclase and produces a time- and concentration-dependent inactivation of all three isoforms of nitric oxide synthase (IC50 = 800 nM, 4 μM, and 5 μM for nNOS, iNOS, and eNOS, respectively). Inhibits relaxation induced by acetylcholine, ANP, and VIP in isolated rat aorta. Blocks interleukin-1 and prevents induction of long-term potentiation. Also useful as an indicator of iron-deficient erythropoiesis. Does not cross the blood-brain barrier. | | Biological Activity | Inhibitor of heme oxygenase, which generates the putative neurotransmitter CO. | | Biochem/physiol Actions | Primary Targetheme oxygenase | | in vivo | Zinc Protoporphyrin (12.5, 25, 50 mg/kg for i.p.; 12.5, 50 mg/kg for p.o.; from day 7 to 19) exerts dose-dependent antitumor effects manifested by the retardation of tumor growth[3].
| Animal Model: | BALB/c mice inoculated with C-26 cells[3] | | Dosage: | 12.5, 25, 50 mg/kg for i.p.; 12.5, 50 mg/kg for p.o. | | Administration: | IP or PO; from day 7 to 19 | | Result: | Exerted dose-dependent antitumor effects manifested by the retardation of tumor growth.
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| | IC 50 | Human Endogenous Metabolite |
| | PROTOPORPHYRINATO ZINC Preparation Products And Raw materials |
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