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Sigma-Aldrich |
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Telenzepine dihydrochloride manufacturers
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| | Telenzepine dihydrochloride Basic information |
| Product Name: | Telenzepine dihydrochloride | | Synonyms: | 4,9-DIHYDRO-3-METHYL-4-[(4-METHYL-1-PIPERAZINYL)ACETYL]-10H-THIENO[3,4-B][1,5] BENZODIAZEPIN-10-ONE DIHYDROCHLORIDE;TELENZEPINE DIHYDROCHLORIDE SELECTIVE M1 MUSCARIN;4,9-Dihydro-3-methyl-4-((4-methyl-1-piperazinyl)acetyl)-(10H)thieno[3,4-b][1,5]benzodiazepin-10-onedihydrochloride;Telenzepine dihydrochloide;Telenzepine hydrate dihydrochloride;4,9-Dihydro-3-methyl-4-((4-methyl-1-piperazinyl)acetyl)-(10H);JTQJFSQQHGPLOX-UHFFFAOYSA-N;TelenzepineHydrochloride | | CAS: | 147416-96-4 | | MF: | C19H22N4O2S | | MW: | 370.47 | | EINECS: | | | Product Categories: | Acetylcholine receptor | | Mol File: | 147416-96-4.mol |  |
| | Telenzepine dihydrochloride Chemical Properties |
| storage temp. | Store at RT | | solubility | H2O: >10 mg/mL | | form | solid | | color | white | | Water Solubility | Soluble to 100 mM in water | | InChI | 1S/C19H22N4O2S.2ClH.H2O/c1-13-18-14(12-26-13)19(25)20-15-5-3-4-6-16(15)23(18)17(24)11-22-9-7-21(2)8-10-22;;;/h3-6,12H,7-11H2,1-2H3,(H,20,25);2*1H;1H2 | | InChIKey | HZWCRPGARSMPNS-UHFFFAOYSA-N | | SMILES | O.Cl.Cl.CN1CCN(CC1)CC(=O)N2c3ccccc3NC(=O)c4csc(C)c24 |
| WGK Germany | 3 | | Storage Class | 11 - Combustible Solids |
| | Telenzepine dihydrochloride Usage And Synthesis |
| Uses | Antiulcerative;M1 muscarinic antagonist | | Uses | Telenzepine dihydrochloride is a potent and selective muscarnic receptor antagonist. | | Uses | Telenzepine dihydrochloride hydrate was used to study M1 muscarinic receptor-mediated signaling in juvenile rat hippocampus and rat urinary bladder. | | Biological Activity | Selective high affinity muscarinic M 1 receptor antagonist (K i = 0.94 nM). Inhibits gastric acid secretion. | | Biochem/physiol Actions | Telenzepine is an analog of pirenzepine and inhibits the secretion of gastric acid. It is an antagonist to M1-receptor and targets the oxyntic gastric glands and the salivary glands. | | storage | Desiccate at RT |
| | Telenzepine dihydrochloride Preparation Products And Raw materials |
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