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| | 4-(2-Methoxyphenyl)benzaldehyde Basic information |
| Product Name: | 4-(2-Methoxyphenyl)benzaldehyde | | Synonyms: | AKOS BAR-0190;2'-METHOXY[1,1'-BIPHENYL]-4-CARBALDEHYDE;2'-METHOXY[1,1'-BIPHENYL]-4-CARBOXALDEHYDE;2'-METHOXY-BIPHENYL-4-CARBALDEHYDE;2'-METHOXY-BIPHENYL-4-CARBOXALDEHYDE;TIMTEC-BB SBB010158;4-(2-Methoxyphenyl)benzaldehyde, 2-(4-Formylphenyl)anisole, 4-Formyl-2-methoxybiphenyl;2'-methoxy-[1,1'-biphenyl]-4-carbaldehyde | | CAS: | 421553-62-0 | | MF: | C14H12O2 | | MW: | 212.24 | | EINECS: | | | Product Categories: | pharmacetical | | Mol File: | 421553-62-0.mol |  |
| | 4-(2-Methoxyphenyl)benzaldehyde Chemical Properties |
| Hazard Codes | Xi | | HazardClass | IRRITANT | | HS Code | 2913000090 |
| | 4-(2-Methoxyphenyl)benzaldehyde Usage And Synthesis |
| Uses | 2''-Methoxy-biphenyl-4-carbaldehyde | | Synthesis | The general procedure for the synthesis of 2'-methoxybiphenyl-4-carbaldehyde from 2-methoxyphenylboronic acid and p-bromobenzaldehyde is as follows: to a round-bottomed flask fitted with a stirring magnet are added 2-methoxyphenylboronic acid (275 mmol), p-bromobenzaldehyde (250 mmol), a base (375 mmol), a catalyst of 1.0 mol/L (9.2 mg), and a solvent (4 mL) . The flask inlet was sealed with a rubber septum and the internal air was displaced by nitrogen. The reaction mixture was stirred at room temperature for a certain time and then diluted with deionized water (5 mL) and ether (5 mL). The organic layer was separated and concentrated under reduced pressure. | | References | [1] Journal of Chemical Research, 2004, # 9, p. 593 - 595
[2] Advanced Synthesis and Catalysis, 2004, vol. 346, # 13-15, p. 1669 - 1673
[3] Synthesis, 2005, # 4, p. 537 - 542
[4] Tetrahedron Letters, 2018, vol. 59, # 31, p. 2989 - 2993
[5] ChemCatChem, 2016, vol. 8, # 4, p. 743 - 750 |
| | 4-(2-Methoxyphenyl)benzaldehyde Preparation Products And Raw materials |
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