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| | ANTI-MOUSE FLK-1 Basic information |
| Product Name: | ANTI-MOUSE FLK-1 | | Synonyms: | Anti-KDR antibody produced in rabbit;Anti-Vascular Endothelial Growth Factor Receptor 2 antibody produced in goat;ANTI-FLK1;ANTI-LY-73;ANTI-MOUSE FLK-1;ANTI-MOUSE LY-73;ANTI-MOUSE VEGF RECEPTOR;ANTI-MOUSE VEGF-R2 | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![ANTI-MOUSE FLK-1 Structure]() |
| | ANTI-MOUSE FLK-1 Chemical Properties |
| storage temp. | -20°C | | form | lyophilized powder | | biological source | rabbit |
| WGK Germany | WGK 1 | | Storage Class | 11 - Combustible Solids |
| | ANTI-MOUSE FLK-1 Usage And Synthesis |
| Uses | Anti-Vascular Endothelial Growth Factor Receptor 2 antibody may be used in immunoblotting at a working concentration of 0.1-0.2 μg/ml. For flow cytometry the recommended concentration is 3-10 μg/ml. The immunohistochemistry of cells and tissues, a working concentration of 5-15 μg/ml may be used. For neutralization reactions, ND50 of 0.1-0.3 μg/ml is recommended. | | General Description | Vascular endothelial growth factors receptors (VEGF Rs) are receptor tyrosine kinases that bind to VEGF that plays important role in embryonic vasculogenesis, angiogenesis and homeostasis. VEGF R2 has the ability to form heterodimers with VEGF R1 and VEGF R3. The binding of VEGF to VEGF R2 results in activation of tyrosine amino acids of the cytoplasmic tail of the receptor. This interaction results in the activation of MAPK, PI3K, PKC, FAK and Src kinase pathways. The biological roles of VEGF R2 include in epithelial cell growth, proliferation, survival, migration and vascular permeability and angiogenesis. Due to its role in promoting migration and angiogenesis, VEGF R2 has been implicated in breast and prostate cancer
Anti-Vascular Endothelial Growth Factor Receptor-2 recognizes mouse VEGF R2. |
| | ANTI-MOUSE FLK-1 Preparation Products And Raw materials |
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