| Company Name: |
SPIRO PHARMA |
| Tel: |
|
| Email: |
eric_feng1954@126.com |
- AA26-9
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- $72.00
-
2026-07-27
- CAS:1312782-34-5
- Purity: 99.88%
- Supply Ability: 10g
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| | Methanone, 1-pyrrolidinyl-1H-1,2,3-triazol-1-yl- Basic information |
| Product Name: | Methanone, 1-pyrrolidinyl-1H-1,2,3-triazol-1-yl- | | Synonyms: | Methanone, 1-pyrrolidinyl-1H-1,2,3-triazol-1-yl-;Pyrrolidin-1-yl-[1,2,3]triazol-1-yl-methanone;AA26-9;peptidases,thioesterases,AA26-9,Phospholipase,AA269,serine,esterases,AA-26-9,AA26 9,Inhibitor,lipases,amidases,inhibit,cell;AA26-8;Pyrrolidin-1-yl(1H-1,2,3-triazol-1-yl)methanone;AA26-9, 10 mM in DMSO | | CAS: | 1312782-34-5 | | MF: | C7H10N4O | | MW: | 166.18 | | EINECS: | | | Product Categories: | | | Mol File: | 1312782-34-5.mol |  |
| | Methanone, 1-pyrrolidinyl-1H-1,2,3-triazol-1-yl- Chemical Properties |
| Boiling point | 306.7±25.0 °C(Predicted) | | density | 1.42±0.1 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | solubility | DMSO:100.0(Max Conc. mg/mL);601.76(Max Conc. mM) | | form | A solid | | pka | -0.71±0.70(Predicted) | | color | White to off-white |
| | Methanone, 1-pyrrolidinyl-1H-1,2,3-triazol-1-yl- Usage And Synthesis |
| Uses | AA26-9 is a potent and broad spectrum serine hydrolase inhibitor. AA26-9 targets included serine peptidases, lipases, amidases, esterases, and thioesterases. AA26-9 shows inhibitory activity against approximately 1/3 of the 40+ serine hydrolases detected in immortalized T cell lines [1][2]. | | References | [1] Adibekian A, et al. Click-generated triazole ureas as ultrapotent in vivo-active serine hydrolase inhibitors. Nat Chem Biol. 2011 May 15;7(7):469-78. DOI:10.1038/nchembio.579
[2] Borne AL, et al. Deciphering T Cell Immunometabolism with Activity-Based Protein Profiling. Curr Top Microbiol Immunol. 2019;420:175-210. DOI:10.1007/82_2018_124 |
| | Methanone, 1-pyrrolidinyl-1H-1,2,3-triazol-1-yl- Preparation Products And Raw materials |
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