Methylamino-PEG4-t-butylester manufacturers
- MeNH-PEG4-COOtBu
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2025-06-07
- CAS:1621616-14-5
- Min. Order: 5g
- Purity: >98.00%
- Supply Ability: 5g
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| | Methylamino-PEG4-t-butylester Basic information |
| Product Name: | Methylamino-PEG4-t-butylester | | Synonyms: | Methylamino-PEG4-t-butylester;Methylamino-PEG5-t-butyl
ester;CAS_1621616-14-5;MeNH-PEG4-CH2CH2COOtBu;Methylamino-PEG4-Boc;4,7,10,13-Tetraoxa-16-azaheptadecanoic acid, 1,1-dimethylethyl ester;tert-Butyl 5,8,11,14-tetraoxa-2-azaheptadecan-17-oate;MeNH-PEG4-COOtBu | | CAS: | 1621616-14-5 | | MF: | C16H33NO6 | | MW: | 335.44 | | EINECS: | | | Product Categories: | | | Mol File: | 1621616-14-5.mol |  |
| | Methylamino-PEG4-t-butylester Chemical Properties |
| Boiling point | 401.7±35.0 °C(Predicted) | | density | 1.015±0.06 g/cm3(Predicted) | | storage temp. | Storage temp. 2-8°C | | solubility | Soluble in Water, DMSO, DCM, DMF | | pka | 9.52±0.10(Predicted) | | form | Liquid | | color | Colorless to light yellow |
| | Methylamino-PEG4-t-butylester Usage And Synthesis |
| Description | Methylamino-PEG4-t-butyl ester is a PEG linker containing a methylamine group and a t-butyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The methylamine group is reactive with carboxylic acids, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions. | | Uses | Methylamino-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs; Alkyl/ether | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | Methylamino-PEG4-t-butylester Preparation Products And Raw materials |
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