5,8,11,14-Tetraoxa-2-azaheptadecanedioic acid, 17-(1,1-dimethylethyl) 1-(9H-fluoren-9-ylmethyl) ester

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5,8,11,14-Tetraoxa-2-azaheptadecanedioic acid, 17-(1,1-dimethylethyl) 1-(9H-fluoren-9-ylmethyl) ester manufacturers
5,8,11,14-Tetraoxa-2-azaheptadecanedioic acid, 17-(1,1-dimethylethyl) 1-(9H-fluoren-9-ylmethyl) ester Basic information
Product Name:5,8,11,14-Tetraoxa-2-azaheptadecanedioic acid, 17-(1,1-dimethylethyl) 1-(9H-fluoren-9-ylmethyl) ester
Synonyms:5,8,11,14-Tetraoxa-2-azaheptadecanedioic acid, 17-(1,1-dimethylethyl) 1-(9H-fluoren-9-ylmethyl) ester;FmocNH-PEG4-t-butyl ester;tert-butyl 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azanonadecan-19-oate;FmocNH-PEG4-COOtBu
CAS:2148295-94-5
MF:C30H41NO8
MW:543.65
EINECS:
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Mol File:2148295-94-5.mol
5,8,11,14-Tetraoxa-2-azaheptadecanedioic acid, 17-(1,1-dimethylethyl) 1-(9H-fluoren-9-ylmethyl) ester Structure
5,8,11,14-Tetraoxa-2-azaheptadecanedioic acid, 17-(1,1-dimethylethyl) 1-(9H-fluoren-9-ylmethyl) ester Chemical Properties
Boiling point 666.6±55.0 °C(Predicted)
density 1.145±0.06 g/cm3(Predicted)
storage temp. Storage temp. 2-8°C
form Liquid
pka11.60±0.46(Predicted)
color Colorless to light yellow
Safety Information
MSDS Information
5,8,11,14-Tetraoxa-2-azaheptadecanedioic acid, 17-(1,1-dimethylethyl) 1-(9H-fluoren-9-ylmethyl) ester Usage And Synthesis
UsesFmocNH-PEG4-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50PEGs
References[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
5,8,11,14-Tetraoxa-2-azaheptadecanedioic acid, 17-(1,1-dimethylethyl) 1-(9H-fluoren-9-ylmethyl) ester Preparation Products And Raw materials
Tag:5,8,11,14-Tetraoxa-2-azaheptadecanedioic acid, 17-(1,1-dimethylethyl) 1-(9H-fluoren-9-ylmethyl) ester(2148295-94-5) Related Product Information
H2N-PEG4-tBu Methylamino-PEG4-t-butylester 5,8,11,14-Tetraoxa-2-azaheptadecanedioic acid, 1,17-bis(1,1-dimethylethyl) ester Fmoc-NH-PEG4-CH2CH2COOH Fmoc-NH-PEG8-CH2CH2COOH Fmoc-12-amino-4,7,10-trioxadodecanoic acid