m-PEG8-NHS ester

m-PEG8-NHS ester Suppliers list

Company Name:	Shanxi Tihondan Pharmaceutical Technology Co., Ltd
Tel:	+8618235132063
Email:	sales@tihondan.com
Products Intro:	Product Name:2,5-Dioxopyrrolidin-1-yl 2,5,8,11,14,17,20,23-octaoxahexacosan-26-oate CAS:756525-90-3 Purity:98%+ Package:50g;100g;500g

Company Name:	Changsha Morning Shine Co., Ltd.
Tel:	+8619973113652
Email:	info@csmspharm.com
Products Intro:	Product Name:m-PEG8-NHS ester;m-PEG7-NHS ester CAS:756525-90-3 Purity:＞98% Package:10g;100g;1kg Remarks:Homologous impurities: ≤0.10% (PEG4–12), ≤0.15% (PEG16–24); PEG24 batch capacity: >50 kg; Process wi

Company Name:	LAURENT
Tel:	+8618100176782
Email:	sun@laurentpeg.com
Products Intro:	Product Name:mPEG7-CH2CH2COONHS ester CAS:756525-90-3 Purity:98% Package:1g;\|100g;\|1000g;

Company Name:	9i LLC
Tel:	+18039569191
Email:	MWan@NiNeiLab.com
Products Intro:	Product Name:mPEG7-CH2CH2COONHS Ester CAS:756525-90-3 Purity:min.97% Package:345USD/1 g Remarks:NA211

Company Name:	Accela ChemBio Inc.
Tel:	+1-858-6993322
Email:	info@accelachem.com
Products Intro:	Product Name:m-PEG8-NHS Ester CAS:756525-90-3 Purity:>97% Package:0.1g;0.25g;1g;5g;10g Remarks:SY055420

m-PEG8-NHS ester manufacturers

m-PEG8-NHS ester Basic information

Product Name:	m-PEG8-NHS ester
Synonyms:	MPEG7-NHS;MPEG7-CH2CH2COONHS Ester;Methyl-PEG8-NHS Ester;1-[(1-Oxo-4,7,10,13,16,19,22,25-octaoxahexacos-1-yl)oxy]-2,5-pyrrolidinedione;4,7,10,13,16,19,22,25-Octaoxahexacosanoic acid 2,5-dioxo-1-pyrrolidinyl ester;Methyl-PEG₈-NHS Ester;m-PEG8-NHS ester;MeO-dPEG(8)-NHS
CAS:	756525-90-3
MF:	C22H39NO12
MW:	509.54
EINECS:
Product Categories:
Mol File:	756525-90-3.mol

m-PEG8-NHS ester Chemical Properties

storage temp.	-20°C
solubility	Soluble in DMSO, DCM, DMF
form	solid or viscous liquid
color	Colorless to Yellow
InChI	InChI=1S/C22H39NO12/c1-27-6-7-29-10-11-31-14-15-33-18-19-34-17-16-32-13-12-30-9-8-28-5-4-22(26)35-23-20(24)2-3-21(23)25/h2-19H2,1H3
InChIKey	IBZNTYBFTKFSMU-UHFFFAOYSA-N
SMILES	C(ON1C(=O)CCC1=O)(=O)CCOCCOCCOCCOCCOCCOCCOCCOC
CAS DataBase Reference	756525-90-3

Safety Information

MSDS Information

m-PEG8-NHS ester Usage And Synthesis

Description	m-PEG8-NHS ester is a PEG linker containing an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The hydrophilic PEG spacer increases solubility in aqueous media.
Uses	m-PEG8-NHS ester is a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
reaction suitability	reagent type: chemical modification reagent reagent type: cross-linking reagent reactivity: amine reactive
in vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References	[1] By Boehnke, et al. Preparation of antibody drug conjugates with NAMPT inhibitors for use in treatment of cancer. Patent WO2019149637A1.

m-PEG8-NHS ester Preparation Products And Raw materials

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