YK-3-237

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YK-3-237 Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:YK-3-237
CAS:1215281-19-8
Purity:96.38% Package:2mg;34USD|5mg;55USD|10mg;89USD
Company Name: HANGZHOU CLAP TECHNOLOGY CO.,LTD
Tel: 86-571-88216897,88216896 13588875226
Email: sales@hzclap.com
Products Intro: Product Name:YK-3-237
CAS:1215281-19-8
Purity:22999% Package:10kg 25kg 200 kilograms per barrel Remarks:good
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354;
Email: support@targetmol.com
Products Intro: Product Name:YK-3-237；B-[2-Methoxy-5-[(1E)-3-oxo-3-(3,4,5-trimethoxyphenyl)-1-propen-1-yl]phenyl]boronic acid
CAS:1215281-19-8
Package:1 mg；1 mL * 10mM (in DMSO)；10 mg；100 mg；200 mg；25 mg；5 mg；50 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Aladdin Scientific
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Email: tp@aladdinsci.com
Products Intro: Product Name:YK 3-237
CAS:1215281-19-8
Purity:>=98%(HPLC) Package:$68.9/5mg;$107.9/10mg;$226.9/25mg;$385.9/50mg;$672.9/100mg;$1514.9/250mg;Bulk pa Remarks:98%(HPLC)
Company Name: Pharmacodia (Beijing) Co.,Ltd  
Tel: +86-400-851-9921
Email: sales@pharmacodia.com
Products Intro: Product Name:YK-3-237
CAS:1215281-19-8
Package:10Mg-100g

YK-3-237 manufacturers

  • YK-3-237
  • YK-3-237 pictures
  • $33.00 / 5mg
  • 2026-04-16
  • CAS:1215281-19-8
  • Min. Order:
  • Purity: 99.47%
  • Supply Ability: 10g
YK-3-237 Basic information
Product Name:YK-3-237
Synonyms:B-[2-Methoxy-5-[(1E)-3-oxo-3-(3,4,5-trimethoxyphenyl)-1-propen-1-yl]phenyl]boronic acid;YK3237,inhibit,Sirtuin,p53,breast,cancer,triple-negative,mtp53,Mutant,TNBC,Inhibitor,deacetylation,YK 3 237;Boronic acid, B-[2-methoxy-5-[(1E)-3-oxo-3-(3,4,5-trimethoxyphenyl)-1-propen-1-yl]phenyl]-;(E)-(2-Methoxy-5-(3-oxo-3-(3,4,5-trimethoxyphenyl)prop-1-en-1-yl)phenyl)boronic acid;YK-3-237, 10 mM in DMSO;YK 3-237 ，E0394
CAS:1215281-19-8
MF:C19H21BO7
MW:372.18
EINECS:
Product Categories:
Mol File:1215281-19-8.mol
YK-3-237 Structure
YK-3-237 Chemical Properties
Boiling point 616.2±65.0 °C(Predicted)
density 1.26±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 10 mg/ml
form A crystalline solid
pka8.08±0.58(Predicted)
color White to light yellow
Safety Information
WGK Germany WGK 3
Storage Class11 - Combustible Solids
MSDS Information
YK-3-237 Usage And Synthesis
UsesYK 3-237, is a sirtuin-1 (SIRT1) activator, and inhibits proliferation of breast cancer cell lines inducing G2/M cell cycle arrest and apoptosis.
Biological ActivityYK-3-237 is an activator of sirtuin-1 (SIRT1). YK-3-237 showed anti-proliferative activity toward triple-negative breast cancer, inducing G2/M cell cycle arrest and apoptosis. In a study on renal fibrosis, YK-3-237 caused enhanced expression of α-SMA and fibronectin, suggesting th at long-term use of SIRT1 activators may increase the risk or progression of chronic kidney disease.
IC 50SIRT1
YK-3-237 Preparation Products And Raw materials
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